e-Drug3D

748

cas 87679-37-6

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS

ROUTE (list)

ORAL

PK parameters

F 10 PERCENT
Tmax 1 HOUR
VD 18 LITER
Cl 52 LITER / HOUR
PPB 80 PERCENT
t1/2 6 HOUR

MW 429.52
NB_atoms 31
XLogP 1.44
PSA 90.442
NB_HD 1
NB_HA 7
fsp3 0.62
Lipinski(0=no;1=yes) 1

FDA
NDA 020528 (pdf not found) INN (TRANDOLAPRIL) MAVIK (ABBVIE) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 020591 (pdf not found) INN (TRANDOLAPRIL ; VERAPAMIL HYDROCHLORIDE) TARKA (ABBVIE) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 077489 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (TEVA PHARMS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077256 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077307 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077522 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (LUPIN) APPROVAL= AP YEAR= 2007
NDA 077805 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (WATSON LABS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078320 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (INVAGEN PHARMS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078438 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007
NDA 078346 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (PHARMOBEDIENT) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078493 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (SENORES PHARMS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078508 (pdf not found) INN (TRANDOLAPRIL) TRANDOLAPRIL (EPIC PHARMA) APPROVAL= AP YEAR= 2008
NDA 079135 (pdf not found) INN (TRANDOLAPRIL ; VERAPAMIL HYDROCHLORIDE) TRANDOLAPRIL AND VERAPAMIL HYDROCHLORIDE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2010