e-Drug3D
738
SEVOFLURANE
INN
SEVOFLURANE
cas 28523-86-6
CLASS
NERVOUS SYSTEM
ANESTHETICS
ROUTE (list)
INHALATION
ATC code
N01AB08
PK parameters
Solubility
SLIGHTLY SOLUBLE IN WATER
TARGET VOLTAGE-GATED SODIUM CHANNELS (NAV)
Glycine receptor subunit alpha-1 UNIPROT P23415 GLRA1
Potassium channel subfamily K member 2 UNIPROT O95069 KCNK2
Formula:
C4H3F7O
Calculated chemical properties:
MW 200.06
NB_atoms 12
XLogP 2.42
PSA 10.426
NB_HD 0
NB_HA 1
fsp3 1.00
Lipinski(0=no;1=yes) 1
NB_atoms 12
XLogP 2.42
PSA 10.426
NB_HD 0
NB_HA 1
fsp3 1.00
Lipinski(0=no;1=yes) 1
FDA
NDA 020478 (label) INN (SEVOFLURANE) ULTANE (ABBVIE) APPROVAL= AP YEAR= 1995
NDA 075895 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 2002
NDA 077867 (pdf not found) INN (SEVOFLURANE) SOJOURN (PIRAMAL CRITICAL) APPROVAL= AP YEAR= 2007
NDA 078650 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (HALOCARBON PRODS) APPROVAL= AP YEAR= 2007
NDA 203793 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (SHANGHAI HENGRUI) APPROVAL= AP YEAR= 2015
NDA 214382 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (SHANDONG) APPROVAL= AP YEAR= 2023
NDA 020478 (label) INN (SEVOFLURANE) ULTANE (ABBVIE) APPROVAL= AP YEAR= 1995
NDA 075895 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 2002
NDA 077867 (pdf not found) INN (SEVOFLURANE) SOJOURN (PIRAMAL CRITICAL) APPROVAL= AP YEAR= 2007
NDA 078650 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (HALOCARBON PRODS) APPROVAL= AP YEAR= 2007
NDA 203793 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (SHANGHAI HENGRUI) APPROVAL= AP YEAR= 2015
NDA 214382 (pdf not found) INN (SEVOFLURANE) SEVOFLURANE (SHANDONG) APPROVAL= AP YEAR= 2023