e-Drug3D

737

RIMEXOLONE

DISCONTINUED

INN
RIMEXOLONE

cas 49697-38-3

CLASS

SENSORY
ANTIINFLAMMATORY
CORTICOSTEROIDS

ROUTE (list)

OPHTHALMIC

PK parameters

t1/2 1.5 HOUR

Solubility

INSOLUBLE IN WATER

Target

TARGET GLUCOCORTICOID RECEPTOR

Glucocorticoid receptor UNIPROT P04150 NR3C1

Download SDF file

(10R,11S,13S,16R,17S)-11-hydroxy-10,13,16,17-tetramethyl-17-propanoyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

Formula:
C24H34O3

Calculated chemical properties:

MW 370.51
NB_atoms 27
XLogP 4.50
PSA 45.417
NB_HD 1
NB_HA 3
fsp3 0.75
Lipinski(0=no;1=yes) 1

FDA
NDA 020474 (pdf not found) INN (RIMEXOLONE) VEXOL (HARROW EYE) APPROVAL= AP YEAR= 1994 DISCONTINUED