e-Drug3D

725

cas 51322-75-9

CLASS

MUSCULO-SKELETAL SYSTEM
ADRENERGIC ALPHA-AGONISTS
ANTIHYPERTENSIVE

ROUTE (list)

ORAL

PK parameters

F 40 PERCENT
VD 156 LITER (65 KILOGRAM)
Cl 42.9 LITER / HOUR
PPB 30 PERCENT
t1/2 2.5 HOUR

MW 253.72
NB_atoms 16
XLogP 1.72
PSA 61.438
NB_HD 2
NB_HA 5
fsp3 0.22
Lipinski(0=no;1=yes) 1

FDA
NDA 020397 (label) INN (TIZANIDINE HYDROCHLORIDE) ZANAFLEX (LEGACY PHARMA USA) APPROVAL= AP YEAR= 1996
NDA 021447 (label) INN (TIZANIDINE HYDROCHLORIDE) ZANAFLEX (LEGACY PHARMA USA) APPROVAL= AP YEAR= 2002
NDA 076280 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076283 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076284 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076286 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (DR REDDYS LABS INC) APPROVAL= AP YEAR= 2002
NDA 076347 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2002
NDA 076399 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2002 OBSOLETE
NDA 076281 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (OXFORD PHARMS) APPROVAL= AP YEAR= 2003
NDA 076282 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076354 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2003
NDA 076371 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076416 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (SUN PHARM INDS INC) APPROVAL= AP YEAR= 2003
NDA 076321 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076533 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (APOTEX) APPROVAL= AP YEAR= 2004
NDA 078868 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2012
NDA 091283 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (UNICHEM LABS LTD) APPROVAL= AP YEAR= 2012
NDA 091502 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 207170 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207199 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208622 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 209605 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2017
NDA 208187 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (CADILA) APPROVAL= AP YEAR= 2018
NDA 210021 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (CADILA PHARMS LTD) APPROVAL= AP YEAR= 2019
NDA 210267 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (NOVAST LABS) APPROVAL= AP YEAR= 2019
NDA 211798 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2019
NDA 212196 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2019
NDA 213223 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (ALEMBIC) APPROVAL= AP YEAR= 2020
NDA 213544 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2020
NDA 213798 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2020
NDA 213365 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 216190 (label) INN (TIZANIDINE HYDROCHLORIDE) ONTRALFY (FIDELITY BIOPHARMA) APPROVAL= AP YEAR= 2024
NDA 218920 (pdf not found) INN (TIZANIDINE HYDROCHLORIDE) TIZANIDINE HYDROCHLORIDE (GRAVITI PHARMS) APPROVAL= AP YEAR= 2024