e-Drug3D

718

cas 106685-40-9

CLASS

DERMATOLOGICALS
ANTI-ACNE
RETINOIDS
RETINOIC ACID RECEPTOR AGONIST

ROUTE (list)

TOPICAL

PK parameters

t1/2 17.2 HOUR

MW 411.50
NB_atoms 31
XLogP 5.35
PSA 42.026
NB_HD 0
NB_HA 3
fsp3 0.39
Lipinski(0=no;1=yes) 0

FDA
NDA 020338 (pdf not found) INN (ADAPALENE) DIFFERIN (GALDERMA LABS LP) APPROVAL= AP YEAR= 1996 NEWMOLECULARENTITY DISCONTINUED
NDA 020380 (label) INN (ADAPALENE) DIFFERIN (GALDERMA LABS LP) APPROVAL= AP YEAR= 1996
NDA 020748 (label) INN (ADAPALENE) DIFFERIN (GALDERMA LABS LP) APPROVAL= AP YEAR= 2000
NDA 021753 (label) INN (ADAPALENE) DIFFERIN (GALDERMA LABS LP) APPROVAL= AP YEAR= 2007
NDA 022320 (label) INN (ADAPALENE ; BENZOYL PEROXIDE) EPIDUO (GALDERMA LABS LP) APPROVAL= AP YEAR= 2008
NDA 022502 (label) INN (ADAPALENE) DIFFERIN (GALDERMA LABS LP) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090824 (pdf not found) INN (ADAPALENE) ADAPALENE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2010
NDA 090962 (pdf not found) INN (ADAPALENE) ADAPALENE (P AND L) APPROVAL= AP YEAR= 2010
NDA 091314 (pdf not found) INN (ADAPALENE) ADAPALENE (GLENMARK PHARMS INC) APPROVAL= AP YEAR= 2010
NDA 200298 (pdf not found) INN (ADAPALENE) ADAPALENE (ENCUBE ETHICALS) APPROVAL= AP YEAR= 2012
NDA 201000 (pdf not found) INN (ADAPALENE) ADAPALENE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 2014
NDA 203790 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 207917 (label) INN (ADAPALENE ; BENZOYL PEROXIDE) EPIDUO FORTE (GALDERMA LABS) APPROVAL= AP YEAR= 2015
NDA 204593 (pdf not found) INN (ADAPALENE) ADAPALENE (CALL INC) APPROVAL= AP YEAR= 2016
NDA 208322 (pdf not found) INN (ADAPALENE) ADAPALENE (TARO) APPROVAL= AP YEAR= 2016
NDA 203981 (pdf not found) INN (ADAPALENE) ADAPALENE (CALL INC) APPROVAL= AP YEAR= 2016
NDA 205033 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2018
NDA 206959 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (TARO) APPROVAL= AP YEAR= 2018
NDA 206164 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (ENCUBE) APPROVAL= AP YEAR= 2018
NDA 209148 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (TARO) APPROVAL= AP YEAR= 2018
NDA 208108 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2019
NDA 213508 (pdf not found) INN (ADAPALENE) ADAPALENE (ALEMBIC) APPROVAL= AP YEAR= 2020
NDA 212464 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2022
NDA 209641 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (ACTAVIS LABS UT INC) APPROVAL= AP YEAR= 2022
NDA 214553 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2022
NDA 215940 (pdf not found) INN (ADAPALENE) ADAPALENE (TARO) APPROVAL= AP YEAR= 2022
NDA 214185 (pdf not found) INN (ADAPALENE ; BENZOYL PEROXIDE) ADAPALENE AND BENZOYL PEROXIDE (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 216632 (label) INN (ADAPALENE ; BENZOYL PEROXIDE ; CLINDAMYCIN PHOSPHATE) CABTREO (BAUSCH) APPROVAL= AP YEAR= 2023