e-Drug3D

711

cas 93957-54-1

CLASS

CARDIOVASCULAR
HYPOLIPIDEMIC
HYPOCHOLESTEROLEMIC
HMG-COA REDUCTASE INHIBITORS

ROUTE (list)

ORAL

PK parameters

F 24 PERCENT
Tmax 1 HOUR
VD 22.7 LITER (65 KILOGRAM)
Cl 5.2 LITER / HOUR (EQN)
PPB 98 PERCENT
t1/2 3 HOUR

MW 410.45
NB_atoms 30
XLogP 3.29
PSA 76.51
NB_HD 2
NB_HA 5
fsp3 0.29
Lipinski(0=no;1=yes) 1

FDA
NDA 020261 (label) INN (FLUVASTATIN SODIUM) LESCOL (NOVARTIS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 021192 (label) INN (FLUVASTATIN SODIUM) LESCOL XL (SANDOZ) APPROVAL= AP YEAR= 2000
NDA 078872 (pdf not found) INN (FLUVASTATIN SODIUM) FLUVASTATIN SODIUM (PAR PHARM) APPROVAL= TA YEAR= 2009
NDA 078407 (pdf not found) INN (FLUVASTATIN SODIUM) FLUVASTATIN SODIUM (TEVA PHARMS) APPROVAL= AP YEAR= 2012
NDA 090595 (pdf not found) INN (FLUVASTATIN SODIUM) FLUVASTATIN SODIUM (MYLAN PHARMS INC) APPROVAL= AP YEAR= 2012
NDA 202458 (pdf not found) INN (FLUVASTATIN SODIUM) FLUVASTATIN SODIUM (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 079011 (pdf not found) INN (FLUVASTATIN SODIUM) FLUVASTATIN SODIUM (TEVA PHARMS USA) APPROVAL= AP YEAR= 2016
NDA 209397 (pdf not found) INN (FLUVASTATIN SODIUM) FLUVASTATIN SODIUM (BEIJING) APPROVAL= AP YEAR= 2021