e-Drug3D

710

cas 95233-18-4

CLASS

ANTIPARASITIC
ANTIMALARIAL
ANTIPNEUMOCYSTIS
ANTIINFECTIVE
ANTIPROTOZOAL
ANALOG OF UBIQUINONE
MITOCHONDRIAL ELECTRON TRANSPORT

ROUTE (list)

ORAL

PK parameters

F 47 PERCENT
VD 39 LITER (65 KILOGRAM)
Cl 0.6 LITER / HOUR
PPB 99.9 PERCENT
t1/2 62.5 HOUR

MW 366.82
NB_atoms 26
XLogP 5.35
PSA 49.748
NB_HD 1
NB_HA 3
fsp3 0.27
Lipinski(0=no;1=yes) 0

FDA
NDA 020259 (pdf not found) INN (ATOVAQUONE) MEPRON (GLAXOSMITHKLINE LLC) APPROVAL= AP YEAR= 1992 NEWMOLECULARENTITY DISCONTINUED
NDA 020500 (pdf not found) INN (ATOVAQUONE) MEPRON (GLAXOSMITHKLINE LLC) APPROVAL= AP YEAR= 1995
NDA 021078 (pdf not found) INN (ATOVAQUONE ; PROGUANIL HYDROCHLORIDE) MALARONE (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 2000
NDA 091211 (pdf not found) INN (ATOVAQUONE ; PROGUANIL HYDROCHLORIDE) ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2011
NDA 202362 (pdf not found) INN (ATOVAQUONE ; PROGUANIL HYDROCHLORIDE) ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (MYLAN) APPROVAL= AP YEAR= 2014
NDA 202960 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2014
NDA 207833 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (CHARTWELL RX) APPROVAL= AP YEAR= 2017
NDA 209750 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (APOTEX) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 209105 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (LUPIN LTD) APPROVAL= AP YEAR= 2018
NDA 209685 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (GLENMARK SPECLT) APPROVAL= AP YEAR= 2018
NDA 210692 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (HETERO LABS LTD III) APPROVAL= AP YEAR= 2018
NDA 210510 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (ABHAI LLC) APPROVAL= AP YEAR= 2019
NDA 212918 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (BIONPHARMA) APPROVAL= AP YEAR= 2021
NDA 214272 (pdf not found) INN (ATOVAQUONE) ATOVAQUONE (PAI HOLDINGS) APPROVAL= AP YEAR= 2021