e-Drug3D

706

SPIRAPRIL

DISCONTINUED

INN
SPIRAPRIL

cas 83647-97-6

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS

ROUTE (list)

ORAL

ATC code

C09AA11

PK parameters

Target

TARGET ANGIOTENSIN-CONVERTING ENZYME (ACE)

Angiotensin-converting enzyme UNIPROT P12821 ACE

Download SDF file

(7S)-8-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1,4-dithia-8-azaspiro[4.4]nonane-7-carboxylic acid

Formula:
C22H30N2O5S2

Calculated chemical properties:

MW 465.61
NB_atoms 31
XLogP 1.06
PSA 89.33
NB_HD 1
NB_HA 7
fsp3 0.59
Lipinski(0=no;1=yes) 1

FDA
NDA 020240 (pdf not found) INN (SPIRAPRIL HYDROCHLORIDE) RENORMAX (SCHERING) APPROVAL= - YEAR= 0 DISCONTINUED