e-Drug3D

698

LEVOCABASTINE

DISCONTINUED

INN
LEVOCABASTINE

cas 79516-68-0

CLASS

RESPIRATORY SYSTEM
HISTAMINE H1 ANTAGONISTS

ROUTE (list)

OPHTHALMIC

PK parameters

Target

TARGET HISTAMINE H1 RECEPTOR

Histamine H1 receptor UNIPROT P35367 HRH1

Download SDF file

(3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid

Formula:
C26H29FN2O2

Calculated chemical properties:

MW 419.50
NB_atoms 31
XLogP 3.56
PSA 56.219
NB_HD 0
NB_HA 4
fsp3 0.46
Lipinski(0=no;1=yes) 1

FDA
NDA 020219 (pdf not found) INN (LEVOCABASTINE HYDROCHLORIDE) LIVOSTIN (NOVARTIS) APPROVAL= AP YEAR= 1993 DISCONTINUED