e-Drug3D

690

NILUTAMIDE

INN
NILUTAMIDE

cas 63612-50-0

CLASS

ANTINEOPLASTIC
ANTIANDROGENIC
ANDROGEN RECEPTOR ANTAGONIST

ROUTE (list)

ORAL

ATC code

L02BB02

PK parameters

F 100 PERCENT
PPB 82 PERCENT
t1/2 45 HOUR

Solubility

SLIGHTLY SOLUBLE IN WATER

Target

TARGET ANDROGEN RECEPTOR

DrugCentral

Androgen receptor UNIPROT P10275 AR

Download SDF file

5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione

Formula:
C12H10F3N3O4

Calculated chemical properties:

MW 317.23
NB_atoms 22
XLogP 0
PSA 82.296
NB_HD 1
NB_HA 6
fsp3 0.33
Lipinski(0=no;1=yes) 1

FDA
NDA 020169 (pdf not found) INN (NILUTAMIDE) NILANDRON (ADVANZ PHARMA) APPROVAL= AP YEAR= 1996 NEWMOLECULARENTITY
NDA 207631 (pdf not found) INN (NILUTAMIDE) NILUTAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 2016