e-Drug3D
69
CAFFEINE
INN
CAFFEINE
cas 58-08-2
CLASS
NERVOUS SYSTEM
STIMULANT
ROUTE (list)
ORAL RECTAL INTRAVENOUS
PK parameters
Tmax 1.25 HOUR
VD 39 LITER (65 KILOGRAM)
Cl 5.4 LITER / HOUR (65 KILOGRAM)
PPB 36 PERCENT
t1/2 5 HOUR
Solubility
SPARINGLY SOLUBLE IN WATER
TARGET ADENOSINE RECEPTOR
PDB
5TAU (STRUCTURE OF RABBIT RYR1 (CAFFEINE, ATP, EGTA DATASET, CLASS 3))
Ligand code = CFF (link to the list of PDB complexes)
Download experimental 3D coordinates of CFF with added hydrogens
Adenosine receptor A2a UNIPROT P29274 ADORA2A
Adenosine receptor A1 UNIPROT P30542 ADORA1
Formula:
C8H10N4O2
Calculated chemical properties:
MW 194.20
NB_atoms 14
XLogP -1.03
PSA 51.642
NB_HD 0
NB_HA 6
fsp3 0.38
Lipinski(0=no;1=yes) 1
NB_atoms 14
XLogP -1.03
PSA 51.642
NB_HD 0
NB_HA 6
fsp3 0.38
Lipinski(0=no;1=yes) 1
FDA
NDA 085441 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (IVAX PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087629 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GILBERT LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088825 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GILBERT LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088972 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089023 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) TRIAD (MALLINCKRODT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089102 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) FEMCET (MALLINCKRODT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089115 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) MEDIGESIC PLUS (US CHEM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089448 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (HALSEY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089660 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ESGIC (FOREST PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 006620 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) CAFERGOT (NOVARTIS) APPROVAL= AP YEAR= 1948 DISCONTINUED
NDA 009000 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) CAFERGOT (NOVARTIS) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 010996 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) DARVON COMPOUND (XANODYNE PHARM) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 011483 (pdf not found) INN (ASPIRIN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) SYNALGOS-DC (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 013416 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) NORGESIC (BAUSCH) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 080044 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND 65 (SANDOZ) APPROVAL= AP YEAR= 1970 DISCONTINUED
NDA 084553 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) COMPOUND 65 (ALRA) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017534 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) FIORINAL (ALLERGAN) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 083101 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND-65 (SANDOZ) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 084294 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) CAFERGOT (CHARTWELL RX) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 083077 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND 65 (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085732 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE HYDROCHLORIDE W/ ASPIRIN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086162 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086237 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086710 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086398 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (FOSUN PHARMA) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086562 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) WIGRAINE (ORGANON USA INC) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087048 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (PURACAP PHARM) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086996 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) LANORINAL (SANDOZ) APPROVAL= AP YEAR= 1981
NDA 086231 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 086986 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) LANORINAL (LANNETT) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 086557 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) MIGERGOT (COSETTE) APPROVAL= AP YEAR= 1983
NDA 088616 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ACTAVIS LABS UT INC) APPROVAL= AP YEAR= 1984
NDA 087804 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (SPECGX LLC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088743 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRAHAM DM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088758 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MALLINCKRODT) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088765 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRAHAM DM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089025 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND 65 (TEVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089067 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRAHAM DM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 087628 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ANOQUAN (SHIRE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 088584 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) DHC PLUS (PHARM RES ASSOC) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089007 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1986
NDA 089166 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) SYNALGOS-DC-A (LEITNER PHARMS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089175 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 1987
NDA 089451 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ESGIC-PLUS (MIKART) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089536 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 019429 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) FIORINAL W/CODEINE (ALLERGAN) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 020232 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) FIORICET W/ CODEINE (ACTAVIS LABS UT INC) APPROVAL= AP YEAR= 1992
NDA 074359 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (WATSON LABS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 089718 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 040085 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ESGIC-PLUS (MIKART) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074654 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE (SANDOZ) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074817 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) INVAGESIC (CHARTWELL RX) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 040109 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (MIKART) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 020802 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) EXCEDRIN MIGRAINE RELIEF (HALEON US HOLDINGS) APPROVAL= AP YEAR= 1998
NDA 040261 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 040267 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074951 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (STEVENS J) APPROVAL= AP YEAR= 1998
NDA 075141 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) ORPHENGESIC (GALT PHARMS) APPROVAL= AP YEAR= 1998
NDA 020793 (pdf not found) INN (CAFFEINE CITRATE) CAFCIT (HIKMA) APPROVAL= AP YEAR= 1999
NDA 040316 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (MIKART) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040336 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 074988 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE (STEVENS J) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075351 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (ESJAY PHARMA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040390 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ABLE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 040394 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ABLE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 074911 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) PHRENILIN WITH CAFFEINE AND CODEINE (VALEANT) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075231 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (LGM PHARMA) APPROVAL= AP YEAR= 2001
NDA 075618 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075794 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) ACETAMINOPHEN, ASPIRIN AND CAFFEINE (PERRIGO) APPROVAL= AP YEAR= 2001
NDA 075929 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (AVIV PHARMA) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 040387 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 2003
NDA 040496 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 040511 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (STRIDES PHARMA) APPROVAL= AP YEAR= 2003
NDA 040513 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (VINTAGE PHARMS) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076528 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (ABLE) APPROVAL= AP YEAR= 2003
NDA 040510 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) ERGOTAMINE TARTRATE AND CAFFEINE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076560 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (LGM PHARMA) APPROVAL= AP YEAR= 2004
NDA 040590 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) ERGOTAMINE TARTRATE AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 2005
NDA 040601 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 040637 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (WEST-WARD PHARM CORP) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077233 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (EXELA PHARMA SCIENCE) APPROVAL= AP YEAR= 2006
NDA 077304 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (EXELA PHARMA) APPROVAL= AP YEAR= 2006
NDA 040688 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (WRASER PHARMS LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040701 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (BOCA PHARMA LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077906 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (AM REGENT) APPROVAL= AP YEAR= 2007
NDA 077997 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2007
NDA 078149 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (MPP PHARMA) APPROVAL= AP YEAR= 2007
NDA 078002 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2008
NDA 040864 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRANULES) APPROVAL= AP YEAR= 2008
NDA 040883 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIRROR PHARMS LLC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 040885 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LGM PHARMA) APPROVAL= AP YEAR= 2009
NDA 090064 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (AM REGENT) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090077 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SUN PHARM) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090357 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SUN PHARM) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090827 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SAGENT PHARMS) APPROVAL= AP YEAR= 2012
NDA 091102 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SAGENT PHARMS) APPROVAL= AP YEAR= 2012
NDA 200243 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LANNETT CO INC) APPROVAL= AP YEAR= 2012
NDA 204785 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) TREZIX (KEY THERAP) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 203335 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 205013 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (EUGIA PHARMA) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 204195 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (STRIDES PHARMA) APPROVAL= AP YEAR= 2016
NDA 204209 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE AND DIHYDROCODEINE BITARTRATE (LARKEN LABS INC) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 207118 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (NUVO PHARMS INC) APPROVAL= AP YEAR= 2016
NDA 204984 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ALVOGEN) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 206615 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (KEY THERAP) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207400 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (MICRO LABS) APPROVAL= AP YEAR= 2017
NDA 204733 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 2018
NDA 209587 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LGM PHARMA) APPROVAL= AP YEAR= 2018
NDA 211106 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ABHAI LLC) APPROVAL= AP YEAR= 2018
NDA 210817 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2019
NDA 212082 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LANNETT CO INC) APPROVAL= AP YEAR= 2019
NDA 212083 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LANNETT CO INC) APPROVAL= AP YEAR= 2019
NDA 213202 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (MICRO LABS) APPROVAL= AP YEAR= 2019
NDA 204649 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2020
NDA 211543 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (NESHER PHARMS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213046 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (TARO) APPROVAL= AP YEAR= 2020
NDA 213321 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRANULES) APPROVAL= AP YEAR= 2020
NDA 203647 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (STRIDES PHARMA) APPROVAL= AP YEAR= 2020
NDA 214039 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) ACETAMINOPHEN, ASPIRIN AND CAFFEINE (GRANULES) APPROVAL= AP YEAR= 2021
NDA 205230 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (LGM PHARMA) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214087 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (SENORES PHARMS) APPROVAL= AP YEAR= 2021
NDA 215047 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (NOVAST LABS) APPROVAL= AP YEAR= 2021
NDA 211695 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) ACETAMINOPHEN, ASPIRIN AND CAFFEINE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2022
NDA 215135 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 215138 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (HIKMA) APPROVAL= AP YEAR= 2022
NDA 214287 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (QUAGEN) APPROVAL= AP YEAR= 2024
NDA 214288 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (QUAGEN) APPROVAL= AP YEAR= 2024
NDA 216376 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (QUAGEN) APPROVAL= AP YEAR= 2024
NDA 085441 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (IVAX PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087629 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GILBERT LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088825 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GILBERT LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088972 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089023 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) TRIAD (MALLINCKRODT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089102 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) FEMCET (MALLINCKRODT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089115 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) MEDIGESIC PLUS (US CHEM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089448 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (HALSEY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089660 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ESGIC (FOREST PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 006620 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) CAFERGOT (NOVARTIS) APPROVAL= AP YEAR= 1948 DISCONTINUED
NDA 009000 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) CAFERGOT (NOVARTIS) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 010996 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) DARVON COMPOUND (XANODYNE PHARM) APPROVAL= AP YEAR= 1957 DISCONTINUED
NDA 011483 (pdf not found) INN (ASPIRIN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) SYNALGOS-DC (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1958 DISCONTINUED
NDA 013416 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) NORGESIC (BAUSCH) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 080044 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND 65 (SANDOZ) APPROVAL= AP YEAR= 1970 DISCONTINUED
NDA 084553 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) COMPOUND 65 (ALRA) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 017534 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) FIORINAL (ALLERGAN) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 083101 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND-65 (SANDOZ) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 084294 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) CAFERGOT (CHARTWELL RX) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 083077 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND 65 (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085732 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE HYDROCHLORIDE W/ ASPIRIN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086162 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086237 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086710 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086398 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (FOSUN PHARMA) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086562 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) WIGRAINE (ORGANON USA INC) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087048 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (PURACAP PHARM) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086996 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) LANORINAL (SANDOZ) APPROVAL= AP YEAR= 1981
NDA 086231 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 086986 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) LANORINAL (LANNETT) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 086557 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) MIGERGOT (COSETTE) APPROVAL= AP YEAR= 1983
NDA 088616 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ACTAVIS LABS UT INC) APPROVAL= AP YEAR= 1984
NDA 087804 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (SPECGX LLC) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088743 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRAHAM DM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088758 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MALLINCKRODT) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088765 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRAHAM DM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089025 (pdf not found) INN (ASPIRIN ; CAFFEINE ; PROPOXYPHENE HYDROCHLORIDE) PROPOXYPHENE COMPOUND 65 (TEVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089067 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRAHAM DM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 087628 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ANOQUAN (SHIRE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 088584 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) DHC PLUS (PHARM RES ASSOC) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089007 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 1986
NDA 089166 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) SYNALGOS-DC-A (LEITNER PHARMS) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089175 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 1987
NDA 089451 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ESGIC-PLUS (MIKART) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 089536 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 019429 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) FIORINAL W/CODEINE (ALLERGAN) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 020232 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) FIORICET W/ CODEINE (ACTAVIS LABS UT INC) APPROVAL= AP YEAR= 1992
NDA 074359 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (WATSON LABS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 089718 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 040085 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) ESGIC-PLUS (MIKART) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074654 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE (SANDOZ) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074817 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) INVAGESIC (CHARTWELL RX) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 040109 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (MIKART) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 020802 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) EXCEDRIN MIGRAINE RELIEF (HALEON US HOLDINGS) APPROVAL= AP YEAR= 1998
NDA 040261 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 040267 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (WATSON LABS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074951 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (STEVENS J) APPROVAL= AP YEAR= 1998
NDA 075141 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) ORPHENGESIC (GALT PHARMS) APPROVAL= AP YEAR= 1998
NDA 020793 (pdf not found) INN (CAFFEINE CITRATE) CAFCIT (HIKMA) APPROVAL= AP YEAR= 1999
NDA 040316 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (MIKART) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040336 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 074988 (pdf not found) INN (ASPIRIN ; CAFFEINE ; ORPHENADRINE CITRATE) ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE (STEVENS J) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075351 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (ESJAY PHARMA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040390 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ABLE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 040394 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ABLE) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 074911 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) PHRENILIN WITH CAFFEINE AND CODEINE (VALEANT) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075231 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (LGM PHARMA) APPROVAL= AP YEAR= 2001
NDA 075618 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075794 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) ACETAMINOPHEN, ASPIRIN AND CAFFEINE (PERRIGO) APPROVAL= AP YEAR= 2001
NDA 075929 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (AVIV PHARMA) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 040387 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 2003
NDA 040496 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 040511 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (STRIDES PHARMA) APPROVAL= AP YEAR= 2003
NDA 040513 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (VINTAGE PHARMS) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076528 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (ABLE) APPROVAL= AP YEAR= 2003
NDA 040510 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) ERGOTAMINE TARTRATE AND CAFFEINE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076560 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (LGM PHARMA) APPROVAL= AP YEAR= 2004
NDA 040590 (pdf not found) INN (CAFFEINE ; ERGOTAMINE TARTRATE) ERGOTAMINE TARTRATE AND CAFFEINE (MIKART) APPROVAL= AP YEAR= 2005
NDA 040601 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 040637 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (WEST-WARD PHARM CORP) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077233 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (EXELA PHARMA SCIENCE) APPROVAL= AP YEAR= 2006
NDA 077304 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (EXELA PHARMA) APPROVAL= AP YEAR= 2006
NDA 040688 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (WRASER PHARMS LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040701 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE, AND DIHYDROCODEINE BITARTRATE (BOCA PHARMA LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077906 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (AM REGENT) APPROVAL= AP YEAR= 2007
NDA 077997 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2007
NDA 078149 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (MPP PHARMA) APPROVAL= AP YEAR= 2007
NDA 078002 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2008
NDA 040864 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRANULES) APPROVAL= AP YEAR= 2008
NDA 040883 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (MIRROR PHARMS LLC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 040885 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LGM PHARMA) APPROVAL= AP YEAR= 2009
NDA 090064 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (AM REGENT) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090077 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SUN PHARM) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090357 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SUN PHARM) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090827 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SAGENT PHARMS) APPROVAL= AP YEAR= 2012
NDA 091102 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (SAGENT PHARMS) APPROVAL= AP YEAR= 2012
NDA 200243 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LANNETT CO INC) APPROVAL= AP YEAR= 2012
NDA 204785 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) TREZIX (KEY THERAP) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 203335 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 205013 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (EUGIA PHARMA) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 204195 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (STRIDES PHARMA) APPROVAL= AP YEAR= 2016
NDA 204209 (pdf not found) INN (ACETAMINOPHEN ; CAFFEINE ; DIHYDROCODEINE BITARTRATE) ACETAMINOPHEN, CAFFEINE AND DIHYDROCODEINE BITARTRATE (LARKEN LABS INC) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 207118 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (NUVO PHARMS INC) APPROVAL= AP YEAR= 2016
NDA 204984 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ALVOGEN) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 206615 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (KEY THERAP) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207400 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (MICRO LABS) APPROVAL= AP YEAR= 2017
NDA 204733 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 2018
NDA 209587 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LGM PHARMA) APPROVAL= AP YEAR= 2018
NDA 211106 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (ABHAI LLC) APPROVAL= AP YEAR= 2018
NDA 210817 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (DR REDDYS LABS SA) APPROVAL= AP YEAR= 2019
NDA 212082 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LANNETT CO INC) APPROVAL= AP YEAR= 2019
NDA 212083 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (LANNETT CO INC) APPROVAL= AP YEAR= 2019
NDA 213202 (pdf not found) INN (CAFFEINE CITRATE) CAFFEINE CITRATE (MICRO LABS) APPROVAL= AP YEAR= 2019
NDA 204649 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (STRIDES PHARMA) APPROVAL= AP YEAR= 2020
NDA 211543 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (NESHER PHARMS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 213046 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (TARO) APPROVAL= AP YEAR= 2020
NDA 213321 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (GRANULES) APPROVAL= AP YEAR= 2020
NDA 203647 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (STRIDES PHARMA) APPROVAL= AP YEAR= 2020
NDA 214039 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) ACETAMINOPHEN, ASPIRIN AND CAFFEINE (GRANULES) APPROVAL= AP YEAR= 2021
NDA 205230 (pdf not found) INN (ASPIRIN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ASPIRIN AND CAFFEINE (LGM PHARMA) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214087 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (SENORES PHARMS) APPROVAL= AP YEAR= 2021
NDA 215047 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (NOVAST LABS) APPROVAL= AP YEAR= 2021
NDA 211695 (pdf not found) INN (ACETAMINOPHEN ; ASPIRIN ; CAFFEINE) ACETAMINOPHEN, ASPIRIN AND CAFFEINE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2022
NDA 215135 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (HIKMA) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 215138 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE ; CODEINE PHOSPHATE) BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE (HIKMA) APPROVAL= AP YEAR= 2022
NDA 214287 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (QUAGEN) APPROVAL= AP YEAR= 2024
NDA 214288 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (QUAGEN) APPROVAL= AP YEAR= 2024
NDA 216376 (pdf not found) INN (ACETAMINOPHEN ; BUTALBITAL ; CAFFEINE) BUTALBITAL, ACETAMINOPHEN AND CAFFEINE (QUAGEN) APPROVAL= AP YEAR= 2024