e-Drug3D
688
cas 69655-05-6
CLASS
ANTIINFECTIVES
ANTIVIRAL
ANTI-HIV AGENTS
ANTIMETABOLITES
REVERSE TRANSCRIPTASE INHIBITORS
ROUTE (list)
ORAL
ATC code
J05AF02
PK parameters
F 42 PERCENT
Tmax 0.8 HOUR
VD 70.3 LITER
Cl 50 LITER / HOUR
PPB 5 PERCENT
t1/2 1.5 HOUR
Solubility
IN WATER 27.3 MILLIGRAM / MILLILITER (PH=6)
TARGET REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN)
Reverse transcriptase,RNaseH UNIPROT Q72549 pol
Formula:
C10H12N4O3
Calculated chemical properties:
MW 236.24
NB_atoms 17
XLogP -0.21
PSA 87.326
NB_HD 2
NB_HA 7
fsp3 0.50
Lipinski(0=no;1=yes) 1
NB_atoms 17
XLogP -0.21
PSA 87.326
NB_HD 2
NB_HA 7
fsp3 0.50
Lipinski(0=no;1=yes) 1
FDA
NDA 020154 (pdf not found) INN (DIDANOSINE) VIDEX (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020155 (pdf not found) INN (DIDANOSINE) VIDEX (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020156 (pdf not found) INN (DIDANOSINE) VIDEX (BRISTOL) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 021183 (pdf not found) INN (DIDANOSINE) VIDEX EC (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 077167 (pdf not found) INN (DIDANOSINE) DIDANOSINE (BARR) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 078112 (pdf not found) INN (DIDANOSINE) DIDANOSINE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 090094 (pdf not found) INN (DIDANOSINE) DIDANOSINE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090788 (pdf not found) INN (DIDANOSINE) DIDANOSINE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 077275 (pdf not found) INN (DIDANOSINE) DIDANOSINE (AUROBINDO) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 020154 (pdf not found) INN (DIDANOSINE) VIDEX (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020155 (pdf not found) INN (DIDANOSINE) VIDEX (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020156 (pdf not found) INN (DIDANOSINE) VIDEX (BRISTOL) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 021183 (pdf not found) INN (DIDANOSINE) VIDEX EC (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 077167 (pdf not found) INN (DIDANOSINE) DIDANOSINE (BARR) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 078112 (pdf not found) INN (DIDANOSINE) DIDANOSINE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 090094 (pdf not found) INN (DIDANOSINE) DIDANOSINE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090788 (pdf not found) INN (DIDANOSINE) DIDANOSINE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 077275 (pdf not found) INN (DIDANOSINE) DIDANOSINE (AUROBINDO) APPROVAL= AP YEAR= 2012 DISCONTINUED