e-Drug3D

687

cas 83366-66-9

CLASS

NERVOUS SYSTEM
ANTIDEPRESSANT
ANALGESICS
SEROTONIN AGENTS
5-HYDROXYTRYPTAMINE 2A RECEPTOR ANTAGONIST

ROUTE (list)

ORAL

PK parameters

F 20 PERCENT
Tmax 1 HOUR
VD 35.4 LITER (65 KILOGRAM)
Cl 29.2 LITER / HOUR (65 KILOGRAM)
PPB 99 PERCENT
t1/2 3 HOUR

MW 470.01
NB_atoms 33
XLogP 3.55
PSA 55.988
NB_HD 0
NB_HA 7
fsp3 0.44
Lipinski(0=no;1=yes) 1

FDA
NDA 020152 (label) INN (NEFAZODONE HYDROCHLORIDE) SERZONE (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 075763 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (IVAX SUB TEVA PHARMS) APPROVAL= TA YEAR= 2003
NDA 076037 (label) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (TEVA) APPROVAL= AP YEAR= 2003
NDA 076072 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076073 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076129 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076196 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (ROXANE) APPROVAL= TA YEAR= 2003
NDA 076302 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076309 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (DR REDDYS LABS INC) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 076409 (pdf not found) INN (NEFAZODONE HYDROCHLORIDE) NEFAZODONE HYDROCHLORIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2003 DISCONTINUED