e-Drug3D

679

MIVACURIUM

DISCONTINUED

INN
MIVACURIUM

cas 133814-19-4

CLASS

MUSCULO-SKELETAL
NEUROMUSCULAR NONDEPOLARIZING MUSCLE RELAXANT AGENTS
ANESTHETIC
CHOLINERGIC RECEPTOR ANTAGONIST

ROUTE (list)

INTRAVENOUS INJECTION

ATC code

M03AC10

PK parameters

VD 9.5 LITER (65 KILOGRAM)
Cl 206 LITER / HOUR (65 KILOGRAM)
PPB 30 PERCENT
t1/2 0.03 HOUR

Target

TARGET NICOTINIC ACETYLCHOLINE RECEPTOR (NACHR)

DrugCentral

Acetylcholine receptor UNIPROT P02708 CHRNA1

Download SDF file

bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate

Formula:
C58H80N2O14

Calculated chemical properties:

MW 1029.24
NB_atoms 74
XLogP 9.03
PSA 159.689
NB_HD 0
NB_HA 14
fsp3 0.52
Lipinski(0=no;1=yes) 0

FDA
NDA 020098 (label) INN (MIVACURIUM CHLORIDE) MIVACRON (ABBVIE) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 078562 (label) INN (MIVACURIUM CHLORIDE) MIVACURIUM CHLORIDE (RISING) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 209708 (pdf not found) INN (MIVACURIUM CHLORIDE) MIVACURIUM CHLORIDE (WOODWARD) APPROVAL= AP YEAR= 2021 DISCONTINUED