e-Drug3D

673

cas 86-21-5

CLASS

RESPIRATORY SYSTEM
ANTIHISTAMINIC
ANTI-ALLERGIC AGENTS
ANTIPRURITIC AGENTS
HISTAMINE H1 ANTAGONISTS

ROUTE (list)

OPHTHALMIC

PK parameters

MW 240.34
NB_atoms 18
XLogP 3.17
PSA 15.763
NB_HD 0
NB_HA 2
fsp3 0.31
Lipinski(0=no;1=yes) 1

FDA
NDA 020065 (pdf not found) INN (NAPHAZOLINE HYDROCHLORIDE ; PHENIRAMINE MALEATE) OPCON-A (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1994
NDA 020226 (pdf not found) INN (NAPHAZOLINE HYDROCHLORIDE ; PHENIRAMINE MALEATE) NAPHCON-A (ALCON) APPROVAL= AP YEAR= 1994
NDA 020485 (pdf not found) INN (NAPHAZOLINE HYDROCHLORIDE ; PHENIRAMINE MALEATE) VISINE (JOHNSON AND JOHNSON) APPROVAL= AP YEAR= 1996
NDA 078208 (pdf not found) INN (NAPHAZOLINE HYDROCHLORIDE ; PHENIRAMINE MALEATE) NAPHAZOLINE HYDROCHLORIDE AND PHENIRAMINE MALEATE (ALTAIRE PHARMS INC) APPROVAL= AP YEAR= 2010
NDA 202795 (pdf not found) INN (NAPHAZOLINE HYDROCHLORIDE ; PHENIRAMINE MALEATE) NAPHAZOLINE HYDROCHLORIDE AND PHENIRAMINE MALEATE (RISING) APPROVAL= AP YEAR= 2013