e-Drug3D
66
cas 80-74-0
CLASS
ANTIINFECTIVES
ANTIBACTERIAL
TREATMENT OF URINARY TRACT INFECTIONS
SULFONAMIDES
ROUTE (list)
ORAL
PK parameters
Solubility
PRACTICALLY INSOLUBLE IN WATER
TARGET DIHYDROPTEROATE SYNTHASE
Dihydropteroate synthase UNIPROT P0AC13 folP
Formula:
C13H15N3O4S
Calculated chemical properties:
MW 309.35
NB_atoms 21
XLogP 1.62
PSA 97.548
NB_HD 2
NB_HA 7
fsp3 0.23
Lipinski(0=no;1=yes) 1
NB_atoms 21
XLogP 1.62
PSA 97.548
NB_HD 2
NB_HA 7
fsp3 0.23
Lipinski(0=no;1=yes) 1
FDA
NDA 050599 (pdf not found) INN (ERYTHROMYCIN ESTOLATE ; SULFISOXAZOLE ACETYL) ILOSONE SULFA (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009182 (pdf not found) INN (SULFISOXAZOLE ACETYL) GANTRISIN (ROCHE) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 050529 (pdf not found) INN (ERYTHROMYCIN ETHYLSUCCINATE ; SULFISOXAZOLE ACETYL) PEDIAZOLE (ROSS LABS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 062758 (pdf not found) INN (ERYTHROMYCIN ETHYLSUCCINATE ; SULFISOXAZOLE ACETYL) ERYZOLE (ALRA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 062759 (pdf not found) INN (ERYTHROMYCIN ETHYLSUCCINATE ; SULFISOXAZOLE ACETYL) ERYTHROMYCIN ETHYLSUCCINATE AND SULFISOXAZOLE ACETYL (BARR) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 050599 (pdf not found) INN (ERYTHROMYCIN ESTOLATE ; SULFISOXAZOLE ACETYL) ILOSONE SULFA (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 009182 (pdf not found) INN (SULFISOXAZOLE ACETYL) GANTRISIN (ROCHE) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 050529 (pdf not found) INN (ERYTHROMYCIN ETHYLSUCCINATE ; SULFISOXAZOLE ACETYL) PEDIAZOLE (ROSS LABS) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 062758 (pdf not found) INN (ERYTHROMYCIN ETHYLSUCCINATE ; SULFISOXAZOLE ACETYL) ERYZOLE (ALRA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 062759 (pdf not found) INN (ERYTHROMYCIN ETHYLSUCCINATE ; SULFISOXAZOLE ACETYL) ERYTHROMYCIN ETHYLSUCCINATE AND SULFISOXAZOLE ACETYL (BARR) APPROVAL= AP YEAR= 1988 DISCONTINUED