e-Drug3D

651

METIPRANOLOL

DISCONTINUED

INN
METIPRANOLOL

cas 22664-55-7

CLASS

SENSORY
NON-SELECTIVE BETA-ADRENERGIC RECEPTOR ANTAGONIST
ANTIHYPERTENSIVE AGENTS
GLAUCOMA

ROUTE (list)

OPHTHALMIC

ATC code

S01ED04
C07BA68
S01ED54

PK parameters

Target

TARGET BETA ADRENERGIC RECEPTOR

DrugCentral

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1

Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

Download SDF file

[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]-2,3,6-trimethylphenyl] acetate

Formula:
C17H27NO4

Calculated chemical properties:

MW 309.40
NB_atoms 22
XLogP 2.27
PSA 68.811
NB_HD 2
NB_HA 5
fsp3 0.59
Lipinski(0=no;1=yes) 1

FDA
NDA 019907 (pdf not found) INN (METIPRANOLOL HYDROCHLORIDE) OPTIPRANOLOL (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 075720 (pdf not found) INN (METIPRANOLOL HYDROCHLORIDE) METIPRANOLOL (SANDOZ) APPROVAL= AP YEAR= 2001 DISCONTINUED