e-Drug3D

647

cas 85441-61-8

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITOR

ROUTE (list)

ORAL

PK parameters

F 60 PERCENT
Tmax 1 HOUR
PPB 97 PERCENT

MW 437.50
NB_atoms 32
XLogP 1.23
PSA 86.455
NB_HD 1
NB_HA 7
fsp3 0.40
Lipinski(0=no;1=yes) 1

FDA
NDA 019885 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) ACCUPRIL (PFIZER PHARMS) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020125 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; QUINAPRIL HYDROCHLORIDE) ACCURETIC (PFIZER PHARMS) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 076036 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (MYLAN) APPROVAL= TA YEAR= 2002
NDA 076374 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076459 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076607 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076651 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (MUTUAL PHARMA) APPROVAL= TA YEAR= 2004 OBSOLETE
NDA 076694 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076049 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 076803 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2005
NDA 077093 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (MYLAN) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 076240 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077690 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (LUPIN) APPROVAL= AP YEAR= 2006
NDA 075504 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078450 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007
NDA 078457 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078211 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090800 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 201356 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091524 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (APOTEX) APPROVAL= AP YEAR= 2013
NDA 202725 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2013
NDA 205823 (pdf not found) INN (QUINAPRIL HYDROCHLORIDE) QUINAPRIL HYDROCHLORIDE (PRINSTON INC) APPROVAL= AP YEAR= 2016