e-Drug3D

646

cas 3930-20-9

CLASS

CARDIOVASCULAR
ADRENERGIC BETA RECEPTOR ANTAGONISTS
ANTI-ARRHYTHMIA AGENTS
SYMPATHOLYTICS
TREATMENT OF DOCUMENTED VENTRICULAR ARRHYTHMIAS

ROUTE (list)

ORAL INTRAVENOUS

PK parameters

F 95 PERCENT
Tmax 3 HOUR
VD 84.5 LITER (65 KILOGRAM)
Cl 7.8 LITER / HOUR
PPB 0 PERCENT
t1/2 12 HOUR

MW 272.37
NB_atoms 18
XLogP 1.09
PSA 81.373
NB_HD 3
NB_HA 5
fsp3 0.50
Lipinski(0=no;1=yes) 1

FDA
NDA 019865 (label) INN (SOTALOL HYDROCHLORIDE) BETAPACE (LEGACY PHARMA) APPROVAL= AP YEAR= 1992
NDA 021151 (label) INN (SOTALOL HYDROCHLORIDE) BETAPACE AF (LEGACY PHARMA) APPROVAL= AP YEAR= 2000 NEWAPPLICATION
NDA 075237 (label) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (ESJAY PHARMA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075238 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075366 (label) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075429 (label) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (TEVA) APPROVAL= AP YEAR= 2000
NDA 075663 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (IMPAX PHARMS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075725 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075500 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SORINE (AIPING PHARM INC) APPROVAL= AP YEAR= 2001
NDA 075515 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 076140 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (APOTEX) APPROVAL= AP YEAR= 2002
NDA 075563 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (OXFORD PHARMS) APPROVAL= AP YEAR= 2003
NDA 076214 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (APOTEX) APPROVAL= AP YEAR= 2003
NDA 076576 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076883 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (TEVA) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 077070 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2005
NDA 077616 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2007
NDA 022306 (label) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (ALTATHERA PHARMS LLC) APPROVAL= AP YEAR= 2009
NDA 205108 (label) INN (SOTALOL HYDROCHLORIDE) SOTYLIZE (AZURITY) APPROVAL= AP YEAR= 2014
NDA 207428 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (BEXIMCO PHARMS USA) APPROVAL= AP YEAR= 2016
NDA 207429 (pdf not found) INN (SOTALOL HYDROCHLORIDE) SOTALOL HYDROCHLORIDE (BEXIMCO PHARMS USA) APPROVAL= AP YEAR= 2018