e-Drug3D

642

DAPIPRAZOLE

DISCONTINUED

INN
DAPIPRAZOLE

cas 72822-12-9

CLASS

SENSORY
ANTIGLAUCOMA
ADRENERGIC ALPHA ANTAGONISTS
ANTIMYDRIATICS
ANTIPSYCHOTIC AGENTS
OPHTHALMOLOGICALS

ROUTE (list)

OPHTHALMIC

ATC code

S01EX02

PK parameters

t1/2 5 HOUR (PMID9261765)

Target

TARGET ALPHA-1A ADRENERGIC RECEPTOR
ALPHA-1B ADRENERGIC RECEPTOR
ALPHA-1D ADRENERGIC RECEPTOR

DrugCentral

Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A

Alpha-1D adrenergic receptor UNIPROT P25100 ADRA1D

Download SDF file

3-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,5-a]pyridine

Formula:
C19H27N5

Calculated chemical properties:

MW 325.46
NB_atoms 24
XLogP 2.29
PSA 37.363
NB_HD 0
NB_HA 5
fsp3 0.58
Lipinski(0=no;1=yes) 1

FDA
NDA 019849 (pdf not found) INN (DAPIPRAZOLE HYDROCHLORIDE) DAPIPRAZOLE HYDROCHLORIDE (FERA PHARMS) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 204902 (pdf not found) INN (DAPIPRAZOLE HYDROCHLORIDE) DAPIPRAZOLE HYDROCHLORIDE (BARADAINA LLC) APPROVAL= AP YEAR= 2019 DISCONTINUED