e-Drug3D

641

cas 79617-96-2

CLASS

NERVOUS SYSTEM
ANTIDEPRESSANT
SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIS)

ROUTE (list)

ORAL

PK parameters

Tmax 6.4 HOUR
PPB 98 PERCENT
t1/2 26 HOUR

TARGET SEROTONIN TRANSPORTER

PDB
6F6N (CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH SERTRALINE)

Ligand code = SRE (link to the list of PDB complexes)

Download experimental 3D coordinates of SRE with added hydrogens

MW 306.22
NB_atoms 20
XLogP 5.18
PSA 13.764
NB_HD 1
NB_HA 1
fsp3 0.29
Lipinski(0=no;1=yes) 0

FDA
NDA 019839 (label) INN (SERTRALINE HYDROCHLORIDE) ZOLOFT (VIATRIS) APPROVAL= AP YEAR= 1991
NDA 020990 (label) INN (SERTRALINE HYDROCHLORIDE) ZOLOFT (VIATRIS) APPROVAL= AP YEAR= 1999
NDA 076540 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (MYLAN PHARMS INC) APPROVAL= TA YEAR= 2004
NDA 076944 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (ANDRX PHARMS) APPROVAL= TA YEAR= 2005 OBSOLETE
NDA 075719 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 076465 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 2006
NDA 076934 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (STRIDES PHARMA) APPROVAL= AP YEAR= 2006
NDA 078053 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (RANBAXY LABS LTD) APPROVAL= TA YEAR= 2006
NDA 076442 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2007
NDA 076671 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 076881 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (STRIDES PHARMA) APPROVAL= AP YEAR= 2007
NDA 076882 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (VIWIT PHARM) APPROVAL= AP YEAR= 2007
NDA 077106 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (ZYDUS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077162 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077206 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007
NDA 077299 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077345 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077397 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2007
NDA 077663 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077670 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (LUPIN) APPROVAL= AP YEAR= 2007
NDA 077713 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (APPCO) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077765 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (TORRENT PHARMS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077818 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (ANDA REPOSITORY) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077977 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078108 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (SUN PHARM INDS (IN)) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078403 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (GRANULES) APPROVAL= AP YEAR= 2008
NDA 078626 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078861 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008
NDA 077864 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (HIKMA PHARMS) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078677 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (REYOUNG) APPROVAL= AP YEAR= 2009
NDA 078175 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (OXFORD PHARMS) APPROVAL= AP YEAR= 2010
NDA 202825 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2014
NDA 214790 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2021
NDA 215133 (label) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (ALMATICA) APPROVAL= AP YEAR= 2021
NDA 218853 (pdf not found) INN (SERTRALINE HYDROCHLORIDE) SERTRALINE HYDROCHLORIDE (ZENARA) APPROVAL= AP YEAR= 2025