e-Drug3D

639

cas 72509-76-3

CLASS

CARDIOVASCULAR
VASODILATOR
ANTIHYPERTENSIVE
ANTI-ARRHYTHMIA AGENTS
CALCIUM CHANNEL BLOCKERS
DIHYDROPYRIDINES
S ENANTIOMER MORE ACTIVE

ROUTE (list)

ORAL

PK parameters

F 20 PERCENT
Tmax 4.5 HOUR
VD 650 LITER (65 KILOGRAM)
Cl 48 LITER / HOUR
PPB 99 PERCENT
t1/2 14 HOUR

MW 384.24
NB_atoms 25
XLogP 3.96
PSA 55.083
NB_HD 1
NB_HA 5
fsp3 0.33
Lipinski(0=no;1=yes) 1

FDA
NDA 019834 (pdf not found) INN (FELODIPINE) PLENDIL (ASTRAZENECA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020668 (pdf not found) INN (ENALAPRIL MALEATE ; FELODIPINE) LEXXEL (ASTRAZENECA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 075896 (pdf not found) INN (FELODIPINE) FELODIPINE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 078855 (pdf not found) INN (FELODIPINE) FELODIPINE (MYLAN) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090365 (pdf not found) INN (FELODIPINE) FELODIPINE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2010
NDA 200815 (pdf not found) INN (FELODIPINE) FELODIPINE (PH HEALTH) APPROVAL= AP YEAR= 2011
NDA 202170 (pdf not found) INN (FELODIPINE) FELODIPINE (TORRENT PHARMS LTD) APPROVAL= AP YEAR= 2011
NDA 091484 (pdf not found) INN (FELODIPINE) FELODIPINE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 091200 (pdf not found) INN (FELODIPINE) FELODIPINE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2013
NDA 201964 (pdf not found) INN (FELODIPINE) FELODIPINE (HERITAGE) APPROVAL= AP YEAR= 2013
NDA 203417 (pdf not found) INN (FELODIPINE) FELODIPINE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2013
NDA 203032 (pdf not found) INN (FELODIPINE) FELODIPINE (ORBION PHARMS) APPROVAL= AP YEAR= 2015
NDA 203983 (pdf not found) INN (FELODIPINE) FELODIPINE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 210847 (pdf not found) INN (FELODIPINE) FELODIPINE (YILING) APPROVAL= AP YEAR= 2018
NDA 204800 (pdf not found) INN (FELODIPINE) FELODIPINE (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2019