e-Drug3D

625

OLSALAZINE

INN
OLSALAZINE

cas 15722-48-2

CLASS

METABOLISM
ANTIINFLAMMATORY
GASTROINTESTINAL AGENTS
TREATMENT OF ULCERATIVE COLITIS

ROUTE (list)

ORAL

ATC code

A07EC03

PK parameters

F 2.4 PERCENT
Tmax 1 HOUR
VD 4.5 LITER (65 KILOGRAM)
Cl 4.6 LITER / HOUR (65 KILOGRAM)
PPB 99 PERCENT
t1/2 0.9 HOUR

Solubility

SOLUBLE IN WATER

Target

DrugCentral

Arachidonate 5-lipoxygenase UNIPROT P09917 ALOX5

Peroxisome proliferator-activated receptor gamma UNIPROT P37231 PPARG

Download SDF file

5-[(2Z)-2-(3-carboxy-4-oxo-1-cyclohexa-2,5-dienylidene)hydrazinyl]-2-hydroxybenzoic acid

Formula:
C14H10N2O6

Calculated chemical properties:

MW 300.22
NB_atoms 22
XLogP -1.66
PSA 125.953
NB_HD 2
NB_HA 8
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 019715 (label) INN (OLSALAZINE SODIUM) DIPENTUM (MYLAN SPCLT VIATRIS) APPROVAL= AP YEAR= 1990