e-Drug3D

609

cas 53230-10-7

CLASS

ANTIPARASITIC
ANTIMALARIAL
STRUCTURAL ANALOG OF QUININE

ROUTE (list)

ORAL

PK parameters

F 85 PERCENT
Tmax 17 HOUR
VD 1300 LITER
Cl 1.8 LITER / HOUR
PPB 98 PERCENT
t1/2 504 HOUR

MW 378.32
NB_atoms 26
XLogP 4.45
PSA 37.753
NB_HD 2
NB_HA 3
fsp3 0.47
Lipinski(0=no;1=yes) 1

FDA
NDA 019578 (pdf not found) INN (MEFLOQUINE HYDROCHLORIDE) MEFLOQUINE HYDROCHLORIDE (US ARMY WALTER REED) APPROVAL= AP YEAR= 1989 NEWMOLECULARENTITY DISCONTINUED
NDA 019591 (label) INN (MEFLOQUINE HYDROCHLORIDE) LARIAM (ROCHE) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 076175 (label) INN (MEFLOQUINE HYDROCHLORIDE) MEFLOQUINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2002
NDA 076392 (label) INN (MEFLOQUINE HYDROCHLORIDE) MEFLOQUINE HYDROCHLORIDE (BARR) APPROVAL= AP YEAR= 2003
NDA 076523 (label) INN (MEFLOQUINE HYDROCHLORIDE) MEFLOQUINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2004
NDA 077699 (pdf not found) INN (MEFLOQUINE HYDROCHLORIDE) MEFLOQUINE HYDROCHLORIDE (HIKMA INTL PHARMS) APPROVAL= AP YEAR= 2010 DISCONTINUED