e-Drug3D

603

cas 76963-41-2

CLASS

METABOLISM
HISTAMINE H2 RECEPTOR ANTAGONIST
ANTIHISTAMINE
ANTI-ULCER AGENTS

ROUTE (list)

ORAL

PK parameters

F 70 PERCENT
Tmax 1.75 HOUR
VD 74.7 LITER (65 KILOGRAM)
Cl 50 LITER / HOUR
PPB 35 PERCENT
t1/2 1.5 HOUR

MW 331.48
NB_atoms 21
XLogP 0
PSA 79.686
NB_HD 2
NB_HA 6
fsp3 0.58
Lipinski(0=no;1=yes) 1

FDA
NDA 019508 (pdf not found) INN (NIZATIDINE) AXID (SMITHKLINE BEECHAM) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 020555 (pdf not found) INN (NIZATIDINE) AXID AR (HALEON US HOLDINGS) APPROVAL= AP YEAR= 1996
NDA 075461 (pdf not found) INN (NIZATIDINE) NIZATIDINE (ANI PHARMS) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 075616 (pdf not found) INN (NIZATIDINE) NIZATIDINE (WATSON LABS) APPROVAL= AP YEAR= 2002
NDA 075668 (pdf not found) INN (NIZATIDINE) NIZATIDINE (ANI PHARMS) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 075806 (pdf not found) INN (NIZATIDINE) NIZATIDINE (NORVIUM BIOSCIENCE) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 075934 (pdf not found) INN (NIZATIDINE) NIZATIDINE (MYLAN PHARMS INC) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076178 (pdf not found) INN (NIZATIDINE) NIZATIDINE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2002
NDA 076383 (pdf not found) INN (NIZATIDINE) NIZATIDINE (APOTEX INC) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 021494 (pdf not found) INN (NIZATIDINE) AXID (BRAINTREE) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 077314 (pdf not found) INN (NIZATIDINE) NIZATIDINE (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2005
NDA 090576 (pdf not found) INN (NIZATIDINE) NIZATIDINE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090618 (pdf not found) INN (NIZATIDINE) NIZATIDINE (GLENMARK PHARMS INC) APPROVAL= AP YEAR= 2011 DISCONTINUED