e-Drug3D

593

cas 81147-92-4

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ADRENERGIC (BETA-1) SELECTIVE BLOCKER
ADRENERGIC BETA-ANTAGONISTS

ROUTE (list)

INJECTION INTRAVENOUS

PK parameters

VD 78 LITER (65 KILOGRAM)
Cl 1300 LITER / HOUR (65 KILOGRAM)
PPB 55 PERCENT
t1/2 0.15 HOUR

MW 295.37
NB_atoms 21
XLogP 1.53
PSA 71.253
NB_HD 2
NB_HA 5
fsp3 0.56
Lipinski(0=no;1=yes) 1

FDA
NDA 019386 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) BREVIBLOC (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1986
NDA 073323 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (BEDFORD LABS) APPROVAL= TA YEAR= 2003 OBSOLETE
NDA 073326 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (BEDFORD LABS) APPROVAL= TA YEAR= 2003 OBSOLETE
NDA 076326 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (BEDFORD LABS) APPROVAL= TA YEAR= 2003 OBSOLETE
NDA 076456 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (PHARMAFORCE) APPROVAL= TA YEAR= 2003 OBSOLETE
NDA 076323 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2004
NDA 076474 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 2005
NDA 076573 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 201126 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (AM REGENT) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 205520 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2015
NDA 205703 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE IN PLASTIC CONTAINER (HQ SPCLT PHARMA) APPROVAL= AP YEAR= 2016
NDA 206608 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2018
NDA 207107 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2018
NDA 208538 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (GLAND) APPROVAL= AP YEAR= 2019
NDA 216244 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2022
NDA 214172 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (HQ SPCLT PHARMA) APPROVAL= AP YEAR= 2022
NDA 216603 (pdf not found) INN (ESMOLOL HYDROCHLORIDE) ESMOLOL HYDROCHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2022