e-Drug3D

TOLAZOLINE

DISCONTINUED

INN
TOLAZOLINE

cas 59-98-3

CLASS

CARDIOVASCULAR
VASODILATOR
ADRENERGIC ALPHA ANTAGONISTS
ANTIHYPERTENSIVE AGENTS

ROUTE (list)

INJECTION

PK parameters

Target

TARGET ALPHA ADRENERGIC RECEPTOR

Alpha-2A adrenergic receptor UNIPROT P08913 ADRA2A

Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A

Download SDF file

2-(phenylmethyl)-4,5-dihydro-1H-imidazole

Formula:
C10H12N2

Calculated chemical properties:

MW 160.22
NB_atoms 12
XLogP 1.23
PSA 24.694
NB_HD 1
NB_HA 2
fsp3 0.30
Lipinski(0=no;1=yes) 1

FDA
NDA 006403 (pdf not found) INN (TOLAZOLINE HYDROCHLORIDE) PRISCOLINE (NOVARTIS) APPROVAL= AP YEAR= 1948 DISCONTINUED