e-Drug3D

587

ALFENTANIL

INN
ALFENTANIL

cas 71195-58-9

CLASS

NERVOUS SYSTEM
ANALGESIC
ANESTHETICS
NARCOTICS
OPIATE AGONISTS

ROUTE (list)

INJECTION

ATC code

N01AH02

PK parameters

VD 45.5 LITER (65 KILOGRAM)
Cl 19.5 LITER / HOUR (65 KILOGRAM)
PPB 92 PERCENT
t1/2 1.6 HOUR

Target

TARGET MU-TYPE OPIOID RECEPTOR

DrugCentral

Mu-type opioid receptor UNIPROT P35372 OPRM1

Download SDF file

N-[1-[2-(4-ethyl-5-oxotetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl]-N-phenylpropanamide

Formula:
C21H32N6O3

Calculated chemical properties:

MW 416.53
NB_atoms 30
XLogP 1.38
PSA 78.16
NB_HD 0
NB_HA 9
fsp3 0.62
Lipinski(0=no;1=yes) 1

FDA
NDA 019353 (pdf not found) INN (ALFENTANIL HYDROCHLORIDE) ALFENTA (RISING) APPROVAL= AP YEAR= 1986 NEWMOLECULARENTITY
NDA 075221 (pdf not found) INN (ALFENTANIL HYDROCHLORIDE) ALFENTANIL (HOSPIRA) APPROVAL= AP YEAR= 1999 DISCONTINUED