e-Drug3D
580
cas 59122-46-2
CLASS
METABOLISM
ANTIULCERATIVE
PROSTAGLANDINS
SYNTHETIC PROSTAGLANDIN E1 ANALOG
ROUTE (list)
ORAL
PK parameters
Solubility
SOLUBLE IN WATER
TARGET PROSTAGLANDIN RECEPTOR
Prostaglandin E2 receptor EP3 subtype UNIPROT P43115 PTGER3
Formula:
C22H38O5
Calculated chemical properties:
MW 382.52
NB_atoms 27
XLogP 3.95
PSA 83.23
NB_HD 2
NB_HA 5
fsp3 0.82
Lipinski(0=no;1=yes) 1
NB_atoms 27
XLogP 3.95
PSA 83.23
NB_HD 2
NB_HA 5
fsp3 0.82
Lipinski(0=no;1=yes) 1
FDA
NDA 019268 (pdf not found) INN (MISOPROSTOL) CYTOTEC (PFIZER) APPROVAL= AP YEAR= 1988
NDA 020607 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) ARTHROTEC (PFIZER) APPROVAL= AP YEAR= 1997
NDA 076095 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (ANI PHARMS) APPROVAL= AP YEAR= 2002
NDA 091667 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (NOVEL LABS INC) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 201089 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2012
NDA 200158 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (SANDOZ) APPROVAL= AP YEAR= 2013
NDA 200540 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (EXELA HOLDINGS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 203995 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 210201 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (ACQ PHARMA) APPROVAL= AP YEAR= 2019
NDA 205143 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2020
NDA 204355 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (MICRO LABS) APPROVAL= AP YEAR= 2021
NDA 216872 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (MICRO LABS) APPROVAL= AP YEAR= 2022
NDA 206771 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ZYDUS PHARMS) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 019268 (pdf not found) INN (MISOPROSTOL) CYTOTEC (PFIZER) APPROVAL= AP YEAR= 1988
NDA 020607 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) ARTHROTEC (PFIZER) APPROVAL= AP YEAR= 1997
NDA 076095 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (ANI PHARMS) APPROVAL= AP YEAR= 2002
NDA 091667 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (NOVEL LABS INC) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 201089 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2012
NDA 200158 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (SANDOZ) APPROVAL= AP YEAR= 2013
NDA 200540 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (EXELA HOLDINGS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 203995 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 210201 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (ACQ PHARMA) APPROVAL= AP YEAR= 2019
NDA 205143 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2020
NDA 204355 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (MICRO LABS) APPROVAL= AP YEAR= 2021
NDA 216872 (pdf not found) INN (MISOPROSTOL) MISOPROSTOL (MICRO LABS) APPROVAL= AP YEAR= 2022
NDA 206771 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ZYDUS PHARMS) APPROVAL= AP YEAR= 2023 DISCONTINUED