e-Drug3D
579
LEVOBUNOLOL
INN
LEVOBUNOLOL
cas 47141-42-4
CLASS
SENSORY
BETA-ADRENERGIC BLOCKER
ANTIGLAUCOMA
EENT DRUGS
SYMPATHOLYTICS
LOWERING INTRAOCULAR PRESSURE
ROUTE (list)
OPHTHALMIC
ATC code
S01ED03
PK parameters
Tmax 4 HOUR
TARGET BETA-1 ADRENERGIC RECEPTOR
BETA-2 ADRENERGIC RECEPTOR
Beta-1 adrenergic receptor UNIPROT P08588 ADRB1
Beta-2 adrenergic receptor UNIPROT P07550 ADRB2
Formula:
C17H25NO3
Calculated chemical properties:
MW 291.38
NB_atoms 21
XLogP 2.33
PSA 62.205
NB_HD 2
NB_HA 4
fsp3 0.59
Lipinski(0=no;1=yes) 1
NB_atoms 21
XLogP 2.33
PSA 62.205
NB_HD 2
NB_HA 4
fsp3 0.59
Lipinski(0=no;1=yes) 1
FDA
NDA 019219 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) BETAGAN (ALLERGAN) APPROVAL= AP YEAR= 1985
NDA 019814 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) BETAGAN (ALLERGAN) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 074307 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074326 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1994
NDA 074779 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) AKBETA (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074780 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) AKBETA (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074850 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074851 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (ALCON LABS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 075473 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075475 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 019219 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) BETAGAN (ALLERGAN) APPROVAL= AP YEAR= 1985
NDA 019814 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) BETAGAN (ALLERGAN) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 074307 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074326 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (BAUSCH AND LOMB) APPROVAL= AP YEAR= 1994
NDA 074779 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) AKBETA (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074780 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) AKBETA (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074850 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074851 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (ALCON LABS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 075473 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075475 (pdf not found) INN (LEVOBUNOLOL HYDROCHLORIDE) LEVOBUNOLOL HYDROCHLORIDE (APOTEX INC) APPROVAL= AP YEAR= 2000 DISCONTINUED