e-Drug3D

575

cas 112-24-3

CLASS

ANTI-WILSON'S DISEASE (HEPATOLENTICULAR DEGENERATION) AUTOSOMAL INHERITED METABOLIC DEFECT RESULTING IN AN INABILITY TO MAINTAIN A NEARZERO BALANCE OF COPPER
CHELATING AGENT

ROUTE (list)

ORAL

PK parameters

-

PDB
1DJ6 (COMPLEX OF A Z-DNA HEXAMER, D(CG)3, WITH SYNTHETIC POLYAMINE AT ROOM TEMPERATURE)

Ligand code = 104 (link to the list of PDB complexes)

Download experimental 3D coordinates of 104 with added hydrogens

MW 146.24
NB_atoms 10
XLogP -1.92
PSA 79.904
NB_HD 6
NB_HA 4
fsp3 1.00
Lipinski(0=no;1=yes) 0

FDA
NDA 019194 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) SYPRINE (BAUSCH) APPROVAL= AP YEAR= 1985 NEWMOLECULARENTITY
NDA 207567 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (WATSON LABS TEVA) APPROVAL= AP YEAR= 2018
NDA 210619 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 211134 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (MSN) APPROVAL= AP YEAR= 2019
NDA 211251 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (NAVINTA LLC) APPROVAL= AP YEAR= 2019
NDA 211554 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2019
NDA 209415 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 209731 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) CLOVIQUE (CHARTWELL RX) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210096 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2019
NDA 211076 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (DR REDDYS) APPROVAL= AP YEAR= 2019
NDA 211637 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (LUPIN LTD) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212238 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2020
NDA 209945 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (ECI PHARMS LLC) APPROVAL= AP YEAR= 2021
NDA 212929 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 215760 (pdf not found) INN (TRIENTINE TETRAHYDROCHLORIDE) CUVRIOR (ORPHALAN) APPROVAL= AP YEAR= 2022
NDA 216356 (pdf not found) INN (TRIENTINE HYDROCHLORIDE) TRIENTINE HYDROCHLORIDE (HETERO LABS LTD III) APPROVAL= AP YEAR= 2022