e-Drug3D

567

cas 29110-47-2

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ADRENERGIC ALPHA 2 AGONIST
SYMPATHOLYTICS
TREATMENT OF ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)

ROUTE (list)

ORAL

PK parameters

Tmax 3 HOUR
VD 364 LITER (65 KILOGRAM)
Cl 17.5 LITER / HOUR (65 KILOGRAM)
PPB 70 PERCENT
t1/2 16 HOUR

MW 246.09
NB_atoms 15
XLogP 1.34
PSA 73.279
NB_HD 4
NB_HA 4
fsp3 0.11
Lipinski(0=no;1=yes) 1

FDA
NDA 019032 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) TENEX (PROMIUS PHARMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 074145 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1995
NDA 074673 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1997
NDA 074762 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074796 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 1997
NDA 075109 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (AMNEAL PHARM) APPROVAL= AP YEAR= 1998
NDA 022037 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) INTUNIV (TAKEDA PHARMS USA) APPROVAL= AP YEAR= 2009
NDA 200881 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2012
NDA 201382 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2015
NDA 201408 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (TWI PHARMS) APPROVAL= AP YEAR= 2015
NDA 202568 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2015
NDA 202578 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 202238 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (IMPAX LABS INC) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 205689 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2017
NDA 205430 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (APOTEX) APPROVAL= AP YEAR= 2018
NDA 213428 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2020
NDA 214689 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (UNICHEM) APPROVAL= AP YEAR= 2021
NDA 216399 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (AIPING PHARM INC) APPROVAL= AP YEAR= 2022
NDA 217293 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2023
NDA 216762 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2023
NDA 216828 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (I 3 PHARMS) APPROVAL= AP YEAR= 2023
NDA 217269 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (ALEMBIC) APPROVAL= AP YEAR= 2023
NDA 217638 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (FOSUN WANBANG) APPROVAL= AP YEAR= 2024
NDA 218326 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (XIROMED) APPROVAL= AP YEAR= 2024
NDA 219033 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (UNICHEM) APPROVAL= AP YEAR= 2024
NDA 219689 (pdf not found) INN (GUANFACINE HYDROCHLORIDE) GUANFACINE HYDROCHLORIDE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2025