e-Drug3D

559

cas 41340-25-4

CLASS

MUSCULO-SKELETAL SYSTEM
NSAID
ANTIINFLAMMATORY
CYCLOOXYGENASE INHIBITORS

ROUTE (list)

ORAL

PK parameters

F 100 PERCENT
Tmax 1.3 HOUR
VD 23 LITER
Cl 3 LITER / HOUR
PPB 99 PERCENT
t1/2 6.4 HOUR

TARGET PROSTAGLANDIN G/H SYNTHASE 1
PROSTAGLANDIN G/H SYNTHASE 2

PDB
5V0V (CRYSTAL STRUCTURE OF EQUINE SERUM ALBUMIN COMPLEX WITH ETODOLAC)

Ligand code = 8QS (link to the list of PDB complexes)

Download experimental 3D coordinates of 8QS with added hydrogens

MW 286.34
NB_atoms 21
XLogP 2.05
PSA 54.908
NB_HD 1
NB_HA 4
fsp3 0.47
Lipinski(0=no;1=yes) 1

FDA
NDA 018922 (label) INN (ETODOLAC) LODINE (WYETH PHARMS INC) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020584 (label) INN (ETODOLAC) LODINE XL (WYETH PHARMS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074819 (pdf not found) INN (ETODOLAC) ETODOLAC (OXFORD PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074839 (pdf not found) INN (ETODOLAC) ETODOLAC (SENORES PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074840 (pdf not found) INN (ETODOLAC) ETODOLAC (ANI PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074841 (pdf not found) INN (ETODOLAC) ETODOLAC (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074842 (pdf not found) INN (ETODOLAC) ETODOLAC (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074844 (pdf not found) INN (ETODOLAC) ETODOLAC (ANI PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074846 (pdf not found) INN (ETODOLAC) ETODOLAC (SHREE HARI INTL) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074883 (pdf not found) INN (ETODOLAC) ETODOLAC (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074892 (pdf not found) INN (ETODOLAC) ETODOLAC (WATSON LABS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074899 (pdf not found) INN (ETODOLAC) ETODOLAC (ANI PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074903 (pdf not found) INN (ETODOLAC) ETODOLAC (PANGEA) APPROVAL= AP YEAR= 1997
NDA 074927 (pdf not found) INN (ETODOLAC) ETODOLAC (BIOPHARM) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074932 (pdf not found) INN (ETODOLAC) ETODOLAC (NATCO PHARMA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074942 (pdf not found) INN (ETODOLAC) ETODOLAC (SANDOZ) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 075009 (pdf not found) INN (ETODOLAC) ETODOLAC (TEVA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074929 (label) INN (ETODOLAC) ETODOLAC (BIOPHARM) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075012 (pdf not found) INN (ETODOLAC) ETODOLAC (MYLAN) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075069 (pdf not found) INN (ETODOLAC) ETODOLAC (WATSON LABS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075071 (pdf not found) INN (ETODOLAC) ETODOLAC (MYLAN) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075074 (pdf not found) INN (ETODOLAC) ETODOLAC (TARO PHARM INDS) APPROVAL= AP YEAR= 1998
NDA 075078 (pdf not found) INN (ETODOLAC) ETODOLAC (TARO) APPROVAL= AP YEAR= 1998
NDA 075104 (pdf not found) INN (ETODOLAC) ETODOLAC (NATCO PHARMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075226 (pdf not found) INN (ETODOLAC) ETODOLAC (RANBAXY LABS LTD) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074847 (pdf not found) INN (ETODOLAC) ETODOLAC (TEVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075126 (pdf not found) INN (ETODOLAC) ETODOLAC (ANI PHARMS) APPROVAL= AP YEAR= 1999
NDA 075419 (pdf not found) INN (ETODOLAC) ETODOLAC (APOTEX) APPROVAL= AP YEAR= 2000
NDA 075665 (pdf not found) INN (ETODOLAC) ETODOLAC (TEVA) APPROVAL= AP YEAR= 2000
NDA 075696 (pdf not found) INN (ETODOLAC) ETODOLAC (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075829 (pdf not found) INN (ETODOLAC) ETODOLAC (WATSON LABS FLORIDA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075943 (pdf not found) INN (ETODOLAC) ETODOLAC (ANI PHARMS) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076004 (pdf not found) INN (ETODOLAC) ETODOLAC (APOTEX) APPROVAL= AP YEAR= 2002
NDA 076174 (pdf not found) INN (ETODOLAC) ETODOLAC (TARO) APPROVAL= AP YEAR= 2003
NDA 091134 (pdf not found) INN (ETODOLAC) ETODOLAC (ZYDUS PHARMS) APPROVAL= AP YEAR= 2014
NDA 208834 (pdf not found) INN (ETODOLAC) ETODOLAC (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2018
NDA 209888 (pdf not found) INN (ETODOLAC) ETODOLAC (ADAPTIS) APPROVAL= AP YEAR= 2018
NDA 210704 (pdf not found) INN (ETODOLAC) ETODOLAC (UNICHEM) APPROVAL= AP YEAR= 2020
NDA 212263 (pdf not found) INN (ETODOLAC) ETODOLAC (UNICHEM) APPROVAL= AP YEAR= 2020
NDA 204729 (pdf not found) INN (ETODOLAC) ETODOLAC (IPCA LABS LTD) APPROVAL= AP YEAR= 2024
NDA 205448 (pdf not found) INN (ETODOLAC) ETODOLAC (IPCA LABS LTD) APPROVAL= AP YEAR= 2024