e-Drug3D

544

ANTAZOLINE

DISCONTINUED

INN
ANTAZOLINE

cas 91-75-8

CLASS

RESPIRATORY SYSTEM
ANTI-ALLERGIC

ROUTE (list)

OPHTHALMIC

ATC code

R01AC04
R06AX05

PK parameters

Target

TARGET NMDA RECEPTOR (PMID10974308)
ALPHA 2 ADRENERGIC RECEPTOR

DrugCentral

Histamine H1 receptor UNIPROT P35367 HRH1

Download SDF file

1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-

Formula:
C17H19N3

Calculated chemical properties:

MW 265.35
NB_atoms 20
XLogP 2.69
PSA 27.28
NB_HD 1
NB_HA 3
fsp3 0.24
Lipinski(0=no;1=yes) 1

FDA
NDA 018746 (pdf not found) INN (ANTAZOLINE PHOSPHATE ; NAPHAZOLINE HYDROCHLORIDE) VASOCON-A (NOVARTIS) APPROVAL= AP YEAR= 1990 NEWAPPLICATION DISCONTINUED