e-Drug3D

543

SULCONAZOLE

INN
SULCONAZOLE

cas 61318-90-9

CLASS

DERMATOLOGICALS
ANTIFUNGAL
CYTOCHROME P450 INHIBITOR

ROUTE (list)

TOPICAL

ATC code

D01AC09

PK parameters

Solubility

VERY SLIGHTLY SOLUBLE IN WATER

Target

TARGET CYTOCHROME P450

DrugCentral

Lanosterol 14-alpha demethylase UNIPROT P10613 ERG11

Download SDF file

H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-

Formula:
C18H15Cl3N2S

Calculated chemical properties:

MW 397.74
NB_atoms 24
XLogP 6.52
PSA 13.261
NB_HD 0
NB_HA 2
fsp3 0.17
Lipinski(0=no;1=yes) 0

FDA
NDA 018738 (pdf not found) INN (SULCONAZOLE NITRATE) EXELDERM (JOURNEY) APPROVAL= AP YEAR= 1985 NEWMOLECULARENTITY
NDA 018737 (pdf not found) INN (SULCONAZOLE NITRATE) EXELDERM (JOURNEY) APPROVAL= AP YEAR= 1989