e-Drug3D

540

TRILOSTANE

DISCONTINUED

INN
TRILOSTANE

cas 13647-35-3

CLASS

HORMONE
ANTINEOPLASTIC
ANTIADRENAL
3-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITOR (PMID12209583)

ROUTE (list)

ORAL

ATC code

H02CA01

PK parameters

Target

TARGET 3-BETA-HYDROXYSTEROID DEHYDROGENASE

3 beta-hydroxysteroid dehydrogenase,Delta

type 2 UNIPROT P26439 HSD3B2

Download SDF file

Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4.alpha.,5.alpha.,17.beta.)-

Formula:
C20H27NO3

Calculated chemical properties:

MW 329.43
NB_atoms 24
XLogP 3.47
PSA 71.502
NB_HD 2
NB_HA 4
fsp3 0.85
Lipinski(0=no;1=yes) 1

FDA
NDA 018719 (pdf not found) INN (TRILOSTANE) MODRASTANE (BIOENVISION) APPROVAL= AP YEAR= 1984 NEWMOLECULARENTITY DISCONTINUED