e-Drug3D

538

QUAZEPAM

INN
QUAZEPAM

cas 36735-22-5

CLASS

NERVOUS SYSTEM
HYPNOTIC
ANXIOLYTIC
BENZODIAZEPINES
GABA MODULATORS
SEDATIVES

ROUTE (list)

ORAL

ATC code

N05CD10

PK parameters

Tmax 2 HOUR
PPB 95 PERCENT
t1/2 39 HOUR

Solubility

INSOLUBLE IN WATER

Target

TARGET GAMMA-AMINOBUTYRIC-ACID RECEPTOR

GABA A receptor alpha-1,beta-1,gamma-2 UNIPROT P14867 GABRA1

GABA A receptor alpha-3,beta-1,gamma-2 UNIPROT P18505 GABRB1

Download SDF file

7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione

Formula:
C17H11ClF4N2S

Calculated chemical properties:

MW 386.80
NB_atoms 25
XLogP 5.03
PSA 13.093
NB_HD 0
NB_HA 2
fsp3 0.18
Lipinski(0=no;1=yes) 0

FDA
NDA 018708 (label) INN (QUAZEPAM) DORAL (GALT PHARMS) APPROVAL= AP YEAR= 1985