e-Drug3D

532

NICLOSAMIDE

DISCONTINUED

INN
NICLOSAMIDE

cas 50-65-7

CLASS

ANTIPARASITIC
ANTHELMINTIC
TENIACIDE
INHIBITS OXIDATIVE PHOSPHORYLATION IN MITOCHONDRIA OF THE WORMS RESULTING IN ENERGY DEPLETION

ROUTE (list)

ORAL

ATC code

P02DA01

PK parameters

Target

PDB
8SUR (TMEM16F BOUND WITH NICLOSAMIDE)

Download experimental 3D coordinates of VUT with added hydrogens

Unknown

Download SDF file

Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-

Formula:
C13H8Cl2N2O4

Calculated chemical properties:

MW 327.11
NB_atoms 21
XLogP 3.86
PSA 83.869
NB_HD 2
NB_HA 5
fsp3 0.00
Lipinski(0=no;1=yes) 1

FDA
NDA 018669 (pdf not found) INN (NICLOSAMIDE) NICLOCIDE (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED