e-Drug3D
528
BUPROPION
INN
BUPROPION
cas 34911-55-2
CLASS
NERVOUS SYSTEM
ANTIDEPRESSANT
NON-NICOTINE AID TO SMOKING CESSATION
WEAK DOPAMINE AND NOREPINEPHRINE UPTAKE INHIBITORS
AMINOKETONE CLASS
ROUTE (list)
ORAL
PK parameters
Tmax 2 HOUR
VD 1950 LITER
Cl 209 LITER / HOUR
PPB 84 PERCENT
t1/2 21 HOUR
Solubility
HIGHLY SOLUBLE IN WATER
TARGET DOPAMINE TRANSPORTER
NOREPINEPHRINE TRANSPORTER
NOREPINEPHRINE TRANSPORTER
PDB
8HFL (CRYO-EM STRUCTURE OF HUMAN NOREPINEPHRINE TRANSPORTER NET IN THE PRESENCE OF THE ANTIDEPRESSANT BUPROPION IN AN INWARD-OPEN STATE AT RESOLUTION OF 3.0 ANGSTROM)
Ligand code = 1XR (link to the list of PDB complexes)
Download experimental 3D coordinates of 1XR with added hydrogens
Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2
Sodium-dependent dopamine transporter UNIPROT Q01959 SLC6A3
Formula:
C13H18ClNO
Calculated chemical properties:
MW 239.73
NB_atoms 16
XLogP 3.30
PSA 28.804
NB_HD 1
NB_HA 2
fsp3 0.46
Lipinski(0=no;1=yes) 1
NB_atoms 16
XLogP 3.30
PSA 28.804
NB_HD 1
NB_HA 2
fsp3 0.46
Lipinski(0=no;1=yes) 1
FDA
NDA 018644 (pdf not found) INN (BUPROPION HYDROCHLORIDE) WELLBUTRIN (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 020358 (pdf not found) INN (BUPROPION HYDROCHLORIDE) WELLBUTRIN SR (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1996
NDA 020711 (pdf not found) INN (BUPROPION HYDROCHLORIDE) ZYBAN (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 075310 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (HERITAGE PHARMA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075491 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2000
NDA 075584 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (APNAR PHARMA LP) APPROVAL= AP YEAR= 2000
NDA 075613 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVATECH) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021515 (pdf not found) INN (BUPROPION HYDROCHLORIDE) WELLBUTRIN XL (BAUSCH) APPROVAL= AP YEAR= 2003
NDA 075932 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2003
NDA 075913 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2004
NDA 075914 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2004
NDA 076711 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076834 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 076845 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 076143 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (APOTEX) APPROVAL= AP YEAR= 2006
NDA 077284 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077415 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077715 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2007
NDA 022108 (pdf not found) INN (BUPROPION HYDROBROMIDE) APLENZIN (BAUSCH) APPROVAL= AP YEAR= 2008
NDA 077285 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WATSON LABS INC) APPROVAL= AP YEAR= 2008
NDA 077455 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WATSON LABS INC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077475 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2008
NDA 079094 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2009
NDA 079095 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2009
NDA 078866 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090325 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2010
NDA 090941 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090942 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 091459 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091520 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 022497 (pdf not found) INN (BUPROPION HYDROCHLORIDE) FORFIVO XL (TWI PHARMS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 201331 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WOCKHARDT LTD) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 202189 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WOCKHARDT LTD) APPROVAL= AP YEAR= 2012
NDA 200835 (pdf not found) INN (BUPROPION HYDROBROMIDE) BUPROPION HYDROBROMIDE (WATSON LABS INC) APPROVAL= TA YEAR= 2013
NDA 202774 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202775 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 200063 (pdf not found) INN (BUPROPION HYDROCHLORIDE ; NALTREXONE HYDROCHLORIDE) CONTRAVE (NALPROPION) APPROVAL= AP YEAR= 2014
NDA 200695 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 201567 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2014
NDA 203969 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (TORRENT) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202304 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PRINSTON INC) APPROVAL= AP YEAR= 2015
NDA 205794 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2016
NDA 206674 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206122 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2016
NDA 206556 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206975 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (HERITAGE PHARMA) APPROVAL= AP YEAR= 2016
NDA 090693 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (LUPIN LTD) APPROVAL= AP YEAR= 2017
NDA 207224 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ANBISON LAB) APPROVAL= AP YEAR= 2017
NDA 207459 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207479 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2017
NDA 207389 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208652 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SINOTHERAPEUTICS INC) APPROVAL= AP YEAR= 2017
NDA 210081 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (TWI PHARMS) APPROVAL= AP YEAR= 2017
NDA 203013 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ALEMBIC) APPROVAL= AP YEAR= 2018
NDA 210015 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2018
NDA 210497 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2018
NDA 211347 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2018
NDA 211020 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (GRAVITI PHARMS) APPROVAL= AP YEAR= 2019
NDA 211200 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ZHEJIANG JUTAI PHARM) APPROVAL= AP YEAR= 2019
NDA 207403 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (MICRO LABS) APPROVAL= AP YEAR= 2020
NDA 208606 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (CADILA PHARMS LTD) APPROVAL= AP YEAR= 2020
NDA 200216 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 203650 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 215568 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (GRANULES) APPROVAL= AP YEAR= 2022
NDA 208043 (pdf not found) INN (NALTREXONE HYDROCHLORIDE ; BUPROPION HYDROCHLORIDE) NALTREXONE HYDROCHLORIDE; BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= TA YEAR= 2022
NDA 215430 (pdf not found) INN (BUPROPION HYDROCHLORIDE ; DEXTROMETHORPHAN HYDROBROMIDE) AUVELITY (AXSOME) APPROVAL= AP YEAR= 2022
NDA 216766 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2023
NDA 216800 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ANNORA PHARMA) APPROVAL= AP YEAR= 2023
NDA 218385 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (GRANULES) APPROVAL= AP YEAR= 2024
NDA 207874 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IPCA LABS LTD) APPROVAL= AP YEAR= 2025
NDA 018644 (pdf not found) INN (BUPROPION HYDROCHLORIDE) WELLBUTRIN (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 020358 (pdf not found) INN (BUPROPION HYDROCHLORIDE) WELLBUTRIN SR (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1996
NDA 020711 (pdf not found) INN (BUPROPION HYDROCHLORIDE) ZYBAN (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 075310 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (HERITAGE PHARMA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075491 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2000
NDA 075584 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (APNAR PHARMA LP) APPROVAL= AP YEAR= 2000
NDA 075613 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVATECH) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 021515 (pdf not found) INN (BUPROPION HYDROCHLORIDE) WELLBUTRIN XL (BAUSCH) APPROVAL= AP YEAR= 2003
NDA 075932 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2003
NDA 075913 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2004
NDA 075914 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2004
NDA 076711 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076834 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 076845 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 076143 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (APOTEX) APPROVAL= AP YEAR= 2006
NDA 077284 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077415 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077715 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2007
NDA 022108 (pdf not found) INN (BUPROPION HYDROBROMIDE) APLENZIN (BAUSCH) APPROVAL= AP YEAR= 2008
NDA 077285 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WATSON LABS INC) APPROVAL= AP YEAR= 2008
NDA 077455 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WATSON LABS INC) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077475 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 2008
NDA 079094 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2009
NDA 079095 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2009
NDA 078866 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090325 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2010
NDA 090941 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 090942 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 091459 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091520 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 022497 (pdf not found) INN (BUPROPION HYDROCHLORIDE) FORFIVO XL (TWI PHARMS) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 201331 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WOCKHARDT LTD) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 202189 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (WOCKHARDT LTD) APPROVAL= AP YEAR= 2012
NDA 200835 (pdf not found) INN (BUPROPION HYDROBROMIDE) BUPROPION HYDROBROMIDE (WATSON LABS INC) APPROVAL= TA YEAR= 2013
NDA 202774 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202775 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 200063 (pdf not found) INN (BUPROPION HYDROCHLORIDE ; NALTREXONE HYDROCHLORIDE) CONTRAVE (NALPROPION) APPROVAL= AP YEAR= 2014
NDA 200695 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 201567 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2014
NDA 203969 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (TORRENT) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202304 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (PRINSTON INC) APPROVAL= AP YEAR= 2015
NDA 205794 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2016
NDA 206674 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206122 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2016
NDA 206556 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206975 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (HERITAGE PHARMA) APPROVAL= AP YEAR= 2016
NDA 090693 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (LUPIN LTD) APPROVAL= AP YEAR= 2017
NDA 207224 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ANBISON LAB) APPROVAL= AP YEAR= 2017
NDA 207459 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207479 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2017
NDA 207389 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208652 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SINOTHERAPEUTICS INC) APPROVAL= AP YEAR= 2017
NDA 210081 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (TWI PHARMS) APPROVAL= AP YEAR= 2017
NDA 203013 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ALEMBIC) APPROVAL= AP YEAR= 2018
NDA 210015 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2018
NDA 210497 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2018
NDA 211347 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2018
NDA 211020 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (GRAVITI PHARMS) APPROVAL= AP YEAR= 2019
NDA 211200 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ZHEJIANG JUTAI PHARM) APPROVAL= AP YEAR= 2019
NDA 207403 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (MICRO LABS) APPROVAL= AP YEAR= 2020
NDA 208606 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (CADILA PHARMS LTD) APPROVAL= AP YEAR= 2020
NDA 200216 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 203650 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (SUN PHARM) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 215568 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (GRANULES) APPROVAL= AP YEAR= 2022
NDA 208043 (pdf not found) INN (NALTREXONE HYDROCHLORIDE ; BUPROPION HYDROCHLORIDE) NALTREXONE HYDROCHLORIDE; BUPROPION HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= TA YEAR= 2022
NDA 215430 (pdf not found) INN (BUPROPION HYDROCHLORIDE ; DEXTROMETHORPHAN HYDROBROMIDE) AUVELITY (AXSOME) APPROVAL= AP YEAR= 2022
NDA 216766 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2023
NDA 216800 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (ANNORA PHARMA) APPROVAL= AP YEAR= 2023
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NDA 207874 (pdf not found) INN (BUPROPION HYDROCHLORIDE) BUPROPION HYDROCHLORIDE (IPCA LABS LTD) APPROVAL= AP YEAR= 2025