e-Drug3D

518

CARPROFEN

DISCONTINUED

INN
CARPROFEN

cas 53716-49-7

CLASS

ANTIINFLAMMATORY
CYCLOOXYGENASE INHIBITOR

ROUTE (list)

ORAL

ATC code

PK parameters

Target

TARGET PROSTAGLANDIN G/H SYNTHASE 2

PDB
5RH4 (PANDDA ANALYSIS GROUP DEPOSITION SARS-COV-2 MAIN PROTEASE FRAGMENT SCREEN -- CRYSTAL STRUCTURE OF SARS-COV-2 MAIN PROTEASE IN COMPLEX WITH Z1530425063 (MPRO-X2659))

Ligand code = UHG (link to the list of PDB complexes)

Download experimental 3D coordinates of UHG with added hydrogens

DrugCentral

Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2

Download SDF file

2-(6-chloro-9H-carbazol-2-yl)propanoic acid

Formula:
C15H12ClNO2

Calculated chemical properties:

MW 272.70
NB_atoms 19
XLogP 2.83
PSA 48.471
NB_HD 1
NB_HA 3
fsp3 0.13
Lipinski(0=no;1=yes) 1

FDA
NDA 018550 (pdf not found) INN (CARPROFEN) RIMADYL (ROCHE) APPROVAL= AP YEAR= 1987 NEWMOLECULARENTITY DISCONTINUED