e-Drug3D

517

cas 26807-65-8

CLASS

CARDIOVASCULAR
DIURETIC
ANTIHYPERTENSIVE
DECREASES SERUM POTASSIUM

ROUTE (list)

ORAL

PK parameters

F 100 PERCENT
Tmax 2 HOUR
PPB 75 PERCENT
t1/2 14 HOUR

TARGET ION CHANNELS

PDB
3BL1 (CARBONIC ANHYDRASE INHIBITORS. SULFONAMIDE DIURETICS REVISITED OLD LEADS FOR NEW APPLICATIONS)

Ligand code = BL1 (link to the list of PDB complexes)

Download experimental 3D coordinates of BL1 with added hydrogens

MW 365.84
NB_atoms 24
XLogP 2.08
PSA 90.933
NB_HD 3
NB_HA 6
fsp3 0.19
Lipinski(0=no;1=yes) 1

FDA
NDA 074665 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (TEVA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018538 (pdf not found) INN (INDAPAMIDE) LOZOL (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 074299 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 1995
NDA 074461 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (RISING) APPROVAL= AP YEAR= 1996
NDA 074498 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074585 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (WATSON LABS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074594 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074722 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 1996
NDA 075105 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075201 (pdf not found) INN (INDAPAMIDE) INDAPAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 219423 (pdf not found) INN (AMLODIPINE BESYLATE ; INDAPAMIDE ; TELMISARTAN) WIDAPLIK (GEORGE MEDICINES) APPROVAL= AP YEAR= 2025 DISCONTINUED