e-Drug3D

500

TOCAINIDE

DISCONTINUED

INN
TOCAINIDE

cas 41708-72-9

CLASS

CARDIOVASCULAR
ANTI-ARRHYTHMIA AGENTS
SODIUM CHANNEL BLOCKERS

ROUTE (list)

ORAL

ATC code

C01BB03

PK parameters

F 100 PERCENT
Tmax 1.25 HOUR
VD 117 LITER
Cl 8.5 LITER / HOUR
PPB 10 PERCENT
t1/2 15 HOUR

Solubility

FREELY SOLUBLE IN WATER

Target

TARGET SODIUM CHANNEL PROTEIN

Sodium channel alpha subunit UNIPROT P35498 SCN1A

Download SDF file

2-amino-N-(2,6-dimethylphenyl)propanamide

Formula:
C11H16N2O

Calculated chemical properties:

MW 192.26
NB_atoms 14
XLogP 1.59
PSA 50.043
NB_HD 3
NB_HA 3
fsp3 0.36
Lipinski(0=no;1=yes) 1

FDA
NDA 018257 (pdf not found) INN (TOCAINIDE HYDROCHLORIDE) TONOCARD (ASTRAZENECA) APPROVAL= AP YEAR= 1984 DISCONTINUED