e-Drug3D
485
VALPROIC ACID
INN
VALPROIC ACID
DIVALPROEX
VALPROATE
cas 99-66-1
CLASS
NERVOUS SYSTEM
ANTICONVULSANT
ANTIMANIC AGENTS
INCREASE GAMMA-AMINO-BUTYRIC ACID (GABA)ERGIC TRANSMISSION
ROUTE (list)
ORAL INJECTION
ATC code
N03AG01
PK parameters
F 90 PERCENT
Tmax 3.5 HOUR
VD 11 LITER
Cl 0.56 LITER / HOUR
PPB 82 PERCENT
t1/2 12.5 HOUR
Solubility
SLIGHTLY SOLUBLE IN WATER
-
Succinate-semialdehyde dehydrogenase, mitochondrial UNIPROT P51649 ALDH5A1
Formula:
C8H16O2
Calculated chemical properties:
MW 143.20
NB_atoms 10
XLogP 0.95
PSA 30.798
NB_HD 0
NB_HA 2
fsp3 0.88
Lipinski(0=no;1=yes) 1
NB_atoms 10
XLogP 0.95
PSA 30.798
NB_HD 0
NB_HA 2
fsp3 0.88
Lipinski(0=no;1=yes) 1
FDA
NDA 018081 (label) INN (VALPROIC ACID) DEPAKENE (ABBVIE) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 018082 (label) INN (VALPROIC ACID) DEPAKENE (ABBVIE) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 018723 (label) INN (DIVALPROEX SODIUM) DEPAKOTE (ABBVIE) APPROVAL= AP YEAR= 1983
NDA 070431 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070868 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PHARMOBEDIENT CNSLTG) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070195 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (SCHERER RP) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070631 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (UPSHER SMITH LABS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 019680 (label) INN (DIVALPROEX SODIUM) DEPAKOTE (ABBVIE) APPROVAL= AP YEAR= 1989
NDA 019794 (pdf not found) INN (DIVALPROEX SODIUM) DEPAKOTE CP (ABBOTT) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 073229 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (CATALENT) APPROVAL= AP YEAR= 1991
NDA 073178 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (ANI PHARMS) APPROVAL= AP YEAR= 1992
NDA 073484 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (BIONPHARMA) APPROVAL= AP YEAR= 1993
NDA 074060 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (HIKMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020593 (label) INN (VALPROATE SODIUM) DEPACON (ABBVIE) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 075379 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PHARM ASSOC) APPROVAL= AP YEAR= 2000
NDA 075782 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (CHARTWELL RX) APPROVAL= AP YEAR= 2000
NDA 021168 (label) INN (DIVALPROEX SODIUM) DEPAKOTE ER (ABBVIE) APPROVAL= AP YEAR= 2000
NDA 075112 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX (APOTEX INC) APPROVAL= TA YEAR= 2001 OBSOLETE
NDA 020782 (label) INN (DIVALPROEX SODIUM) DEPAKOTE ER (ABBOTT) APPROVAL= AP YEAR= 2002
NDA 076295 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (SAGENT) APPROVAL= AP YEAR= 2002
NDA 076539 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2003
NDA 077105 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PAI HOLDINGS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077143 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX (RANBAXY) APPROVAL= TA YEAR= 2005 OBSOLETE
NDA 077960 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (LANNETT CO INC) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077254 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (MYLAN) APPROVAL= TA YEAR= 2006
NDA 022152 (label) INN (VALPROIC ACID) STAVZOR (BIONPHARMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 022267 (label) INN (DIVALPROEX SODIUM) DEPAKOTE ER (ABBVIE INC) APPROVAL= AP YEAR= 2008 NEWAPPLICATION
NDA 076941 (label) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (TEVA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077296 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 2008
NDA 077615 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (APOTEX) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078182 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2008
NDA 078290 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (INVATECH) APPROVAL= AP YEAR= 2008
NDA 078597 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (SUN PHARM INDS) APPROVAL= AP YEAR= 2008
NDA 078755 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2008
NDA 078790 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (LUPIN) APPROVAL= AP YEAR= 2008
NDA 078411 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PH HEALTH) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078853 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ORBION PHARMS) APPROVAL= AP YEAR= 2008
NDA 077100 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ZYDUS PHARMS USA INC) APPROVAL= AP YEAR= 2009
NDA 077567 (label) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (MYLAN) APPROVAL= AP YEAR= 2009
NDA 078239 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ZYDUS PHARMS USA INC) APPROVAL= AP YEAR= 2009
NDA 078445 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PH HEALTH) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078700 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (COSETTE) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078705 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2009
NDA 078791 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (IMPAX LABS) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078919 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ZYDUS PHARMS USA INC) APPROVAL= AP YEAR= 2009
NDA 078979 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2009
NDA 090062 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090210 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PRINSTON INC) APPROVAL= AP YEAR= 2009
NDA 078523 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2010
NDA 090517 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (QUAGEN) APPROVAL= AP YEAR= 2010
NDA 079080 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 079163 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (UNICHEM LABS LTD) APPROVAL= AP YEAR= 2011
NDA 090407 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (RISING) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 090554 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2011
NDA 090070 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (REDDYS) APPROVAL= AP YEAR= 2012
NDA 090161 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2012
NDA 091037 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202419 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2014
NDA 203730 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2015
NDA 207611 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (HIBROW HLTHCARE) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 209286 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (LUPIN LTD) APPROVAL= AP YEAR= 2019
NDA 213181 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2020
NDA 211505 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (TEVA PHARMS USA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 214462 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 208120 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214643 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (UNICHEM) APPROVAL= AP YEAR= 2022
NDA 215527 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ANNORA PHARMA) APPROVAL= AP YEAR= 2023
NDA 218793 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ALEMBIC) APPROVAL= AP YEAR= 2024
NDA 217358 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (MANKIND PHARMA) APPROVAL= AP YEAR= 2025
NDA 018081 (label) INN (VALPROIC ACID) DEPAKENE (ABBVIE) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 018082 (label) INN (VALPROIC ACID) DEPAKENE (ABBVIE) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 018723 (label) INN (DIVALPROEX SODIUM) DEPAKOTE (ABBVIE) APPROVAL= AP YEAR= 1983
NDA 070431 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PAR PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070868 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PHARMOBEDIENT CNSLTG) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070195 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (SCHERER RP) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 070631 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (UPSHER SMITH LABS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 019680 (label) INN (DIVALPROEX SODIUM) DEPAKOTE (ABBVIE) APPROVAL= AP YEAR= 1989
NDA 019794 (pdf not found) INN (DIVALPROEX SODIUM) DEPAKOTE CP (ABBOTT) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 073229 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (CATALENT) APPROVAL= AP YEAR= 1991
NDA 073178 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (ANI PHARMS) APPROVAL= AP YEAR= 1992
NDA 073484 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (BIONPHARMA) APPROVAL= AP YEAR= 1993
NDA 074060 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (HIKMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020593 (label) INN (VALPROATE SODIUM) DEPACON (ABBVIE) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 075379 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PHARM ASSOC) APPROVAL= AP YEAR= 2000
NDA 075782 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (CHARTWELL RX) APPROVAL= AP YEAR= 2000
NDA 021168 (label) INN (DIVALPROEX SODIUM) DEPAKOTE ER (ABBVIE) APPROVAL= AP YEAR= 2000
NDA 075112 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX (APOTEX INC) APPROVAL= TA YEAR= 2001 OBSOLETE
NDA 020782 (label) INN (DIVALPROEX SODIUM) DEPAKOTE ER (ABBOTT) APPROVAL= AP YEAR= 2002
NDA 076295 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (SAGENT) APPROVAL= AP YEAR= 2002
NDA 076539 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2003
NDA 077105 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (PAI HOLDINGS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077143 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX (RANBAXY) APPROVAL= TA YEAR= 2005 OBSOLETE
NDA 077960 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (LANNETT CO INC) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077254 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (MYLAN) APPROVAL= TA YEAR= 2006
NDA 022152 (label) INN (VALPROIC ACID) STAVZOR (BIONPHARMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 022267 (label) INN (DIVALPROEX SODIUM) DEPAKOTE ER (ABBVIE INC) APPROVAL= AP YEAR= 2008 NEWAPPLICATION
NDA 076941 (label) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (TEVA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077296 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 2008
NDA 077615 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (APOTEX) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078182 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2008
NDA 078290 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (INVATECH) APPROVAL= AP YEAR= 2008
NDA 078597 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (SUN PHARM INDS) APPROVAL= AP YEAR= 2008
NDA 078755 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2008
NDA 078790 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (LUPIN) APPROVAL= AP YEAR= 2008
NDA 078411 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PH HEALTH) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078853 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ORBION PHARMS) APPROVAL= AP YEAR= 2008
NDA 077100 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ZYDUS PHARMS USA INC) APPROVAL= AP YEAR= 2009
NDA 077567 (label) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (MYLAN) APPROVAL= AP YEAR= 2009
NDA 078239 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ZYDUS PHARMS USA INC) APPROVAL= AP YEAR= 2009
NDA 078445 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PH HEALTH) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078700 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (COSETTE) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078705 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (SCIEGEN PHARMS INC) APPROVAL= AP YEAR= 2009
NDA 078791 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (IMPAX LABS) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078919 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ZYDUS PHARMS USA INC) APPROVAL= AP YEAR= 2009
NDA 078979 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2009
NDA 090062 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090210 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (PRINSTON INC) APPROVAL= AP YEAR= 2009
NDA 078523 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2010
NDA 090517 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (QUAGEN) APPROVAL= AP YEAR= 2010
NDA 079080 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 079163 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (UNICHEM LABS LTD) APPROVAL= AP YEAR= 2011
NDA 090407 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (RISING) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 090554 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2011
NDA 090070 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (REDDYS) APPROVAL= AP YEAR= 2012
NDA 090161 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2012
NDA 091037 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202419 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2014
NDA 203730 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2015
NDA 207611 (pdf not found) INN (VALPROIC ACID) VALPROIC ACID (HIBROW HLTHCARE) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 209286 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (LUPIN LTD) APPROVAL= AP YEAR= 2019
NDA 213181 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (AJANTA PHARMA LTD) APPROVAL= AP YEAR= 2020
NDA 211505 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (TEVA PHARMS USA) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 214462 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 208120 (pdf not found) INN (VALPROATE SODIUM) VALPROATE SODIUM (PHARMOBEDIENT) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 214643 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (UNICHEM) APPROVAL= AP YEAR= 2022
NDA 215527 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ANNORA PHARMA) APPROVAL= AP YEAR= 2023
NDA 218793 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (ALEMBIC) APPROVAL= AP YEAR= 2024
NDA 217358 (pdf not found) INN (DIVALPROEX SODIUM) DIVALPROEX SODIUM (MANKIND PHARMA) APPROVAL= AP YEAR= 2025