e-Drug3D

48

cas 59-02-9

CLASS

METABOLISM
ANTIOXIDANTS
VITAMINS
PROTECTS AGAINST FREE RADICAL DAMAGE

ROUTE (list)

INJECTION INTRAVENOUS

PK parameters

TARGET ALPHA-TOCOPHEROL TRANSFER PROTEIN (ALPHA-TTP) (PMID24231105)

PDB
5MUG (SELF-ASSEMBLED ALPHA-TOCOPHEROL TRANSFER PROTEIN NANOPARTICLES PROMOTE VITAMIN E DELIVERY ACROSS AN ENDOTHELIAL BARRIER)

Ligand code = VIV (link to the list of PDB complexes)

Download experimental 3D coordinates of VIV with added hydrogens

MW 430.69
NB_atoms 31
XLogP 8.84
PSA 27.772
NB_HD 1
NB_HA 2
fsp3 0.79
Lipinski(0=no;1=yes) 0

FDA
NDA 018440 (pdf not found) INN (VITAMIN A) M.V.C. 9+3 (ABRAXIS PHARM) APPROVAL= AP YEAR= 0 DISCONTINUED
NDA 018933 (pdf not found) INN (VITAMIN A) M.V.I.-12 LYOPHILIZED (ASTRAZENECA) APPROVAL= AP YEAR= 0 DISCONTINUED
NDA 008809 (pdf not found) INN (RIBOFLAVIN) M.V.I.-12 (HOSPIRA) APPROVAL= AP YEAR= 1953
NDA 018439 (pdf not found) INN (VITAMIN A) MVC PLUS (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 018920 (pdf not found) INN (PHYTONADIONE) M.V.I. PEDIATRIC (HOSPIRA) APPROVAL= AP YEAR= 1983
NDA 006071 (pdf not found) INN (VITAMIN E) BEROCCA PN (ROCHE) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 020176 (pdf not found) INN (PANTOTHENIC ACID) VITAPED (HOSPIRA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 021625 (pdf not found) INN (VITAMIN K) M.V.I. ADULT (HOSPIRA) APPROVAL= AP YEAR= 2004
NDA 021643 (pdf not found) INN (VITAMIN K) M.V.I. ADULT (PHARMACY BULK PACKAGE) (HOSPIRA) APPROVAL= AP YEAR= 2004