e-Drug3D

479

cas 20594-83-6

CLASS

NERVOUS SYSTEM
NARCOTIC
ANALGESIC
KAPPA OPIOID RECEPTOR AGONIST
PARTIAL MU OPIOID RECEPTOR ANTAGONIST

ROUTE (list)

INTRAMUSCULAR INTRAVENOUS SUBCUTANEOUS INJECTION

PK parameters

Tmax 0.041 HOUR
VD 299 LITER (65 KILOGRAM)
Cl 85.8 LITER / HOUR (65 KILOGRAM)
PPB 50 PERCENT
t1/2 5 HOUR

MW 357.44
NB_atoms 26
XLogP 1.71
PSA 73.776
NB_HD 3
NB_HA 5
fsp3 0.71
Lipinski(0=no;1=yes) 1

FDA
NDA 070692 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070693 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072070 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072071 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072072 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072073 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072074 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072075 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018024 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NUBAIN (PH HEALTH) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 070751 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE (ABRAXIS PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070752 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE (ABRAXIS PHARM) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 070914 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1989
NDA 070915 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1989
NDA 070916 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1989
NDA 070917 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (ABBOTT) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 070918 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1989
NDA 020200 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (ABBVIE) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074471 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (DR REDDYS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 206506 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 207595 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 216049 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024
NDA 216050 (pdf not found) INN (NALBUPHINE HYDROCHLORIDE) NALBUPHINE HYDROCHLORIDE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2024