e-Drug3D

476

cas 644-62-2

CLASS

MUSCULO-SKELETAL
ANALGESIC
ANTIINFLAMMATORY
ANTIPYRETIC
CYCLOOXYGENASE INHIBITORS
NSAID

ROUTE (list)

ORAL

PK parameters

Tmax 1.25 HOUR
VD 23.3 LITER
Cl 12.3 LITER / HOUR
PPB 99 PERCENT
t1/2 1.3 HOUR

TARGET PROSTAGLANDIN G/H SYNTHASE 1
LEUKOCYTE 5-LIPOXYGENASE
PROSTAGLANDIN G/H SYNTHASE 2

PDB
5IKQ (THE STRUCTURE OF MECLOFENAMIC ACID BOUND TO HUMAN CYCLOOXYGENASE-2)

Ligand code = JMS (link to the list of PDB complexes)

Download experimental 3D coordinates of JMS with added hydrogens

MW 295.13
NB_atoms 19
XLogP 3.41
PSA 42.49
NB_HD 1
NB_HA 3
fsp3 0.07
Lipinski(0=no;1=yes) 1

FDA
NDA 070400 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 070401 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071007 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071008 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (USL PHARMA) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071362 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (AM THERAP) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071363 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (AM THERAP) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071380 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLODIUM (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071381 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLODIUM (QUANTUM PHARMICS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071640 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071641 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071684 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (VITARINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 071710 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (VITARINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072077 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (PAR PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 072078 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (PAR PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018006 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOMEN (PARKE DAVIS) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 071081 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (MYLAN) APPROVAL= AP YEAR= 1986
NDA 071468 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (ANI PHARMS INC) APPROVAL= AP YEAR= 1987 DISCONTINUED OBSOLETE
NDA 071469 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (ANI PHARMS) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 072262 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 072263 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 072809 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (BARR) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 072848 (pdf not found) INN (MECLOFENAMATE SODIUM) MECLOFENAMATE SODIUM (BARR) APPROVAL= AP YEAR= 1989 DISCONTINUED