e-Drug3D

474

OXAMNIQUINE

DISCONTINUED

INN
OXAMNIQUINE

cas 21738-42-1

CLASS

ANTIPARASITIC
ANTISCHISTOSOMAL
SCHISTOSOMICIDES

ROUTE (list)

ORAL

ATC code

P02BA02

PK parameters

Tmax 1.4 HOUR (PMID3104279)
t1/2 2.2 HOUR

Target

TARGET SULFOTRANSFERASES (PMID17308787)

PDB
5TIX (SCHISTOSOMA HAEMATOBIUM (BLOOD FLUKE) SULFOTRANSFERASE, R-OXAMNIQUINE COMPLEX)

Download experimental 3D coordinates of OQR with added hydrogens

Unknown

Download SDF file

[7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl]methanol

Formula:
C14H21N3O3

Calculated chemical properties:

MW 279.34
NB_atoms 20
XLogP 0
PSA 84.849
NB_HD 3
NB_HA 5
fsp3 0.57
Lipinski(0=no;1=yes) 1

FDA
NDA 018069 (pdf not found) INN (OXAMNIQUINE) VANSIL (PFIZER) APPROVAL= AP YEAR= 1980 NEWMOLECULARENTITY DISCONTINUED