e-Drug3D

472

cas 42200-33-9

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANTIARRHYTHMIC
ANTIANGINAL
ADRENERGIC (BETA) BLOCKER
SYMPATHOLYTICS
BETA-2 ADRENERGIC RECEPTOR INVERSE AGONIST

ROUTE (list)

ORAL

PK parameters

VD 123.5 LITER (65 KILOGRAM)
Cl 11.3 LITER / HOUR (65 KILOGRAM)
PPB 86 PERCENT
t1/2 22 HOUR

MW 309.40
NB_atoms 22
XLogP 0.63
PSA 85.588
NB_HD 4
NB_HA 5
fsp3 0.65
Lipinski(0=no;1=yes) 1

FDA
NDA 018063 (pdf not found) INN (NADOLOL) CORGARD (USWM) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 018647 (pdf not found) INN (BENDROFLUMETHIAZIDE ; NADOLOL) CORZIDE (KING PHARMS LLC) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 074172 (pdf not found) INN (NADOLOL) NADOLOL (RISING) APPROVAL= AP YEAR= 1993
NDA 074368 (pdf not found) INN (NADOLOL) NADOLOL (TEVA PHARMS) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074501 (pdf not found) INN (NADOLOL) NADOLOL (SANDOZ) APPROVAL= AP YEAR= 1995
NDA 074229 (pdf not found) INN (NADOLOL) NADOLOL (HERITAGE PHARMA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074255 (pdf not found) INN (NADOLOL) NADOLOL (HERITAGE PHARMA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 077833 (pdf not found) INN (BENDROFLUMETHIAZIDE ; NADOLOL) NADOLOL AND BENDROFLUMETHIAZIDE (IMPAX LABS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078688 (pdf not found) INN (BENDROFLUMETHIAZIDE ; NADOLOL) NADOLOL AND BENDROFLUMETHIAZIDE (MYLAN) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 201893 (pdf not found) INN (NADOLOL) NADOLOL (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2015
NDA 203455 (pdf not found) INN (NADOLOL) NADOLOL (INVAGEN PHARMS) APPROVAL= AP YEAR= 2015
NDA 207761 (pdf not found) INN (NADOLOL) NADOLOL (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 208832 (pdf not found) INN (NADOLOL) NADOLOL (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2017
NDA 209309 (pdf not found) INN (NADOLOL) NADOLOL (CHARTWELL RX) APPROVAL= AP YEAR= 2017
NDA 210786 (pdf not found) INN (NADOLOL) NADOLOL (NOVAST LABS) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 210955 (pdf not found) INN (NADOLOL) NADOLOL (BEXIMCO PHARMS USA) APPROVAL= AP YEAR= 2018
NDA 212856 (pdf not found) INN (NADOLOL) NADOLOL (RK PHARMA) APPROVAL= AP YEAR= 2019
NDA 211763 (pdf not found) INN (NADOLOL) NADOLOL (ALEMBIC) APPROVAL= AP YEAR= 2023