e-Drug3D

463

cas 42408-82-2

CLASS

NERVOUS SYSTEM
ANTITUSSIVE
ANALGESIC
NARCOTIC ANTAGONISTS
A MIXED AGONIST-ANTAGONIST OF MU-TYPE OPIOID RECEPTOR
AGONIST OF KAPPA-TYPE OPIOID RECEPTOR

ROUTE (list)

INJECTION NASAL

PK parameters

F 65 PERCENT
Tmax 0.5 HOUR
VD 603 LITER
Cl 103 LITER / HOUR
PPB 80 PERCENT
t1/2 4.74 HOUR

MW 327.45
NB_atoms 24
XLogP 3.37
PSA 45.85
NB_HD 2
NB_HA 3
fsp3 0.71
Lipinski(0=no;1=yes) 1

FDA
NDA 017857 (pdf not found) INN (BUTORPHANOL TARTRATE) STADOL PRESERVATIVE FREE (APOTHECON) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 019890 (label) INN (BUTORPHANOL TARTRATE) STADOL (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 074620 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE PRESERVATIVE FREE (HOSPIRA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074626 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE PRESERVATIVE FREE (HOSPIRA) APPROVAL= AP YEAR= 1997
NDA 075045 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE PRESERVATIVE FREE (HIKMA) APPROVAL= AP YEAR= 1998
NDA 075046 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (HIKMA) APPROVAL= AP YEAR= 1998
NDA 075170 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE PRESERVATIVE FREE (HOSPIRA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075342 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (HOSPIRA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075559 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (HOSPIRA) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075695 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE PRESERVATIVE FREE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075697 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075759 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (RISING) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075499 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (APOTEX) APPROVAL= AP YEAR= 2002
NDA 075824 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (HIKMA) APPROVAL= AP YEAR= 2002
NDA 078247 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078400 (pdf not found) INN (BUTORPHANOL TARTRATE) BUTORPHANOL TARTRATE (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2009