e-Drug3D

46

cas 65-23-6

CLASS

METABOLISM
ANTI-INFLAMMATORY AGENTS
VITAMIN B6

ROUTE (list)

INJECTION ORAL INTRAVENOUS

PK parameters

Tmax 5.7 HOUR
t1/2 0.5 HOUR

-

PDB
4C5L (STRUCTURE OF THE PYRIDOXAL KINASE FROM STAPHYLOCOCCUS AUREUS IN COMPLEX WITH PYRIDOXAL)

Ligand code = UEG (link to the list of PDB complexes)

Download experimental 3D coordinates of UEG with added hydrogens

MW 169.18
NB_atoms 12
XLogP 0.08
PSA 71.657
NB_HD 3
NB_HA 4
fsp3 0.38
Lipinski(0=no;1=yes) 1

FDA
NDA 008378 (pdf not found) INN (NIACINAMIDE ; PYRIDOXINE HYDROCHLORIDE ; TYROSINE) TPN (INTL MINERALS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 018933 (pdf not found) INN (PYRIDOXINE) M.V.I.-12 LYOPHILIZED (TELIGENT PHARMA INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080669 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (LUITPOLD) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 083760 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087967 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 006071 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) BEROCCA PN (ROCHE) APPROVAL= AP YEAR= 1947 DISCONTINUED
NDA 008809 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) M.V.I.-12 ADULT (HOSPIRA) APPROVAL= AP YEAR= 1953 DISCONTINUED
NDA 010598 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) BENDECTIN (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1956 DISCONTINUED
NDA 080618 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1972
NDA 080761 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (BEL MAR) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080854 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) HEXA-BETALIN (LILLY) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080572 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (DR REDDYS) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 083771 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (DELL LABS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 018440 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) M.V.C. 9+3 (ABRAXIS PHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 018439 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) MVC PLUS (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 018920 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) M.V.I. PEDIATRIC (HOSPIRA) APPROVAL= AP YEAR= 1983
NDA 080581 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (ELKINS SINN) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 083772 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (DELL LABS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 020176 (pdf not found) INN (PYRIDOXINE) VITAPED (HOSPIRA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 021163 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) INFUVITE ADULT (SANDOZ CANADA INC) APPROVAL= AP YEAR= 2000
NDA 021265 (pdf not found) INN (PYRIDOXINE) INFUVITE PEDIATRIC (SANDOZ CANADA INC) APPROVAL= AP YEAR= 2001
NDA 021559 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) INFUVITE ADULT (SANDOZ INC) APPROVAL= AP YEAR= 2003 OBSOLETE
NDA 021625 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) M.V.I. ADULT (HOSPIRA) APPROVAL= AP YEAR= 2004
NDA 021643 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) M.V.I. ADULT PHARMACY BULK PACKAGE (HOSPIRA) APPROVAL= AP YEAR= 2004 NEWAPPLICATION
NDA 021646 (pdf not found) INN (PYRIDOXINE) INFUVITE PEDIATRIC PHARMACY BULK PACKAGE (SANDOZ INC) APPROVAL= AP YEAR= 2004 OBSOLETE
NDA 021876 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DICLEGIS (DUCHESNAY) APPROVAL= AP YEAR= 2013
NDA 204879 (pdf not found) INN (PYRIDOXINE HYDROCHLORIDE) PYRIDOXINE HYDROCHLORIDE (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 205811 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2016
NDA 209661 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) BONJESTA (DUCHESNAY) APPROVAL= AP YEAR= 2016
NDA 208518 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 2017
NDA 207825 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (MYLAN PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 212472 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 217000 (pdf not found) INN (DOXYLAMINE SUCCINATE ; PYRIDOXINE HYDROCHLORIDE) DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE (BIONPHARMA) APPROVAL= AP YEAR= 2023